摘要
目的建立一种适合溶栓的急性脑梗死模型。方法选用成年家犬31只,经股动脉插管至颈内动脉,用自体血栓栓塞大脑中动脉,数字减影血管造影(DSA)及病理检查证实脑梗死。结果24只犬的脑梗死模型成功建立,成功率达77%。结论通过介入方法建立的自体血栓性脑梗死模型稳定性好,方法简便。
Objective To establish a kind of acute cerebral infarction model for thrombolysis. Methods 31 dogs were collected for Middle Cerebral Artery（MCA） embolization with autologous blood clot by femoral artery punctured and catheterized. Cerebral infarction was demonstrated by DSA examination and pathologicexamination. Results 24 models of cerebral infarction were established with self-thombolus of dogs, the success rate was 77%. Conclusion The cerebral infarction modle with autologous blood clot was good for its stability and easy method by interventional method.
出处
《东南国防医药》
2009年第3期196-198,共3页
Military Medical Journal of Southeast China
关键词
脑梗死
动物模型
自体血栓
Cerebral infarction
Animal model
Autologous blood clot
