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胸腔置管引流并用药物治疗恶性胸腔积液的临床研究 被引量:2

Thoracic cavity perfusion drainage with drugs for treatment of malignant pleural effusion
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摘要 目的观察胸腔置管引流并给予胸腔内注药治疗恶性胸腔积液的疗效。方法100例病人随机分成2组,实验组50例,应用国产中心静脉导管置入胸腔引流积液,并注入平阳霉素、卡铂、干扰素;并与应用传统钢针抽液并注入药物的对照组进行比较。结果实验组总有效率92.0%明显高于对照组58.0%(χ2=7.345,P<0.05)。结论胸腔置管引流并用药治疗恶性胸腔积液疗效好,安全可靠。 Objective To observe the therapeutic effect of infusing chemotherapeutic drugs into cavity for treatment of malignant pleural effusion by cavity central venous catheter. Methods 100 patients with malignant pleural effusion were randomizeded into two groups. 50 patients in the treated group were treated with Pingyangrnycin, carboplatin, and interferon combined with cavity central venous catheter. 50 patients in the control group were treated with pingyangrncycin, carboplatin and interferon by traditionary pneumothorax needle. Results The total effective rate of treatment group 92. 0% was higher than that of the control group 58.0% obviously (X^2 = 7. 345, P 〈 0. 05 ). Conclusion Infusing chemotherapeutic drugs into cavity for treatment of malignant pleural effusion by cavity central venous cathete is more effective and safe.
出处 《滨州医学院学报》 2009年第3期200-202,共3页 Journal of Binzhou Medical University
关键词 胸腔置管引流 卡铂 平阳霉素 干扰素 恶性胸腔积液 malignant pleural effusion,carboplatin,pingyangmycin,IFN,closed thoracic drainage
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