摘要
目的观察抗痫１号（硼砂和苯巴比妥组分比为２５：１）抗实验性惊厥的效果。方法对抗痫１号、苯巴比妥、苯妥英钠分别采用腹腔注射和灌胃给药，观察对抗电惊厥和药物惊厥的效果，并做记录，最后进行统计分析。结果抗痫１号不同剂量的给药组和苯妥英钠、苯巴比妥对抗电惊厥、药物性惊厥相比有明显差异。结论抗痫１号对几种实验性惊厥和腹腔注射抗士的宁惊厥与苛妥英钠相比有明显差异，灌胃给药抗电惊厥和抗士的宁惊厥比安定效果明显：抗痫１号对所有的实验性惊厥比硼砂单独用药效果都有所提高，和苯巴比妥相比，全部苯巴比妥组的小白鼠都烦燥不安，而抗痫１号组的小白鼠无此表现。
bjectives To observe the effects of Num I antiepilepsy compounder(Borax:Phenemal roups 25:1) in mice.Methods Using intraperitioneal injection and perfusion mice have been given Num I antiepilepsy compounder,phenemal and phenytoin respectively.To observe and record the effects of their anti-electric and antimedicinal epilepsy.Results To compare different dose Num I antiepilepsy compounder with phenemal and phenytoin groups,the results shown that there had significant diferent among them.Conclusions Num I antiepilepsy compounder has obvious effection in some antiepilepsy experiment.To compare Num I antiepilipsy compounder which antimetrazol epilepsy and antistrychnine by intraperitioneal injection with phenytoin,the former′s effection was more obvious.The Num I antiepilepsy compounder had more effective than Borax in all experiment.In contrast with phenemal,all mice of phenemal′s group shown restlessness,but another group didn′t.These results show that both have synergistic action.
出处
《宁夏医学杂志》
CAS
1998年第4期226-228,共3页
Ningxia Medical Journal
