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肺癌患者凝血功能改变分析 被引量:17

Coagulation function change in patients with lung cancer
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摘要 目的:观察肺癌患者凝血功能的变化。方法:采用全自动血凝分析仪测定PT、APTT、Fbg,D2聚体。结果:晚期肺癌组PT、APTT明显缩短(P<0.01),D2聚体和Fbg显著升高(P<0.01),其中晚期小细胞肺癌患者升高更明显。结论:晚期肺癌患者多存在高凝状态,小细胞型肺癌尤为明显。 Objective:To observe the coagulation function change in the patients with lung cancer and discuss the relationship of the coagulation function with clinical pathological type and different stages of lung cancer. Methods .We selected 60 patients with lung cancer and 30 healthy subjects. We used an Automatic coagulation analyzer to measure the PT,APTT and Fbg and the synchronous detection of D2 polymer was done. Results:The advanced lung cancer group showed that PT and APTT were significantly reduced (P〈 0.01), and D2 polymer and Fbg were significantly increased (P 〈 0.01), with a more obvious increase in advanced small cell lung cancer patients. Conclusion: Most patients with advanced lung cancer show a hypercoagulable state, more obvious in small cell lung cancer.
出处 《黑龙江医药科学》 2009年第4期49-50,共2页 Heilongjiang Medicine and Pharmacy
基金 佳木斯大学计划项目S34号
关键词 肺癌 高凝状态 lung cancer high-coagulation state
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