摘要
以苯甲醛与VC为原料,N,N-二甲基乙酰胺为溶剂,甲基磺酸为催化剂,环己烷为带水剂,合成了苯甲醛VC缩醛。考察了原料配比、催化剂用量、溶剂用量、回流温度对反应收率的影响。最佳条件为:苯甲醛、VC与甲基磺酸的物质的量的比为1∶1.5∶0.25(摩尔比),溶剂用量0.75 L,回流温度120℃,反应时间4.0 h。产物结构用IR、熔点测定和元素分析确认。
Benzylaldehyde L-ascorbic acid acetal was synthesized using benzylaldehyde and L-ascorbic acid as raw materials and dimethyl acetamide as solvent and methyl sulfonic acid as catalyst and the eyclohexane as dehydrating agent. Factors influencing the yield were investigated. The optimum reaction conditions are as follows ： benzylaldehyde ： L-ascorbic acid ： methyl sulfonic acid is 1 ： 1.5 ：0. 25, amount of solvent is 0.75 L, reflux temperature is 120 ℃, reaction time is 4 h. The title compound was characterized by IR, MS and elemental analysis.
出处
《应用化工》
CAS
CSCD
2009年第6期840-841,846,共3页
Applied Chemical Industry
关键词
甲基磺酸
催化
合成
苯甲醛VC缩醛
methyl sulfonic acid
catalysis
synthesis
benzylaldehyde L-ascorbie acid aeetal
