摘要
目的:研究普米克令舒联合爱全乐雾化吸入对慢性阻塞性肺病急性加重期(AECOPD)的临床疗效。方法:对84例AECOPD住院患者随机分为观察组与对照组。观察组42例,在常规治疗的基础上给予普米克令舒2mg和爱全乐(0.025%溴化异丙托品雾化液)2ml加生理盐水2ml联合雾化吸入治疗,2次/d;对照组42例,在常规治疗的基础上以爱全乐雾化溶液2ml加生理盐水2ml治疗,2次/d,对两组患者用药7d后的临床症状、血气分析及FEV1%变化情况进行比较分析。结果:两组治疗前后PaO2、PaCO2、FEV1%比较,差异有统计学意义(P<0.05),两组间各对应指标相比较,差异均有统计学意义(P<0.05)。两组的年龄、性别、发病、病程等构成情况大致相同。结论:普米克令舒联合爱全乐雾化吸入对AECOPD能迅速缓解病情,畅通呼吸道,改善肺功能,疗效优于单一用药,是治疗AECOPD的有效选择。
Objective： To study the clinical effect of aerosol inhalation theropy of combing Pulmicort respules with Atrovent on AECOPD. Methods： 84 patients with AECOPD were randomized into study group and control group.On the base of norreal treatment, 42 patients were administrated with Pulmicort respules 2 mg and Atrovent atomized solution 2 ml dissolved in saline 2 ml for aerosol inhalation 2 times a day. 42 controls were given only Atrovent atomized solution 2 ml dissolved in saline 2 ml for aerosol inhalation 2 times a day. Then clinical manifestations, blood gas analysis and FEV1% at baseline and 7 days after treatment were determined. Results： There were significant differences in PaO2,PaCO2 and FEV1% between two groups before and after treatment （P〈0.05）. The corresponding indicators between two groups were all significant different （P〈0.05）. And the two groups were in the .same composition of age, sex and course of disease,and so on. Conclusion： Aerosol inhalation theropy of combing Pulmicort respules with Atrovent more effective than Atrovent on AECOPD.
出处
《中国当代医药》
2009年第14期7-8,共2页
China Modern Medicine
