摘要
目的:建立桂枝茯苓丸的微生物限度检查法。方法:通过常规平皿法及培养基稀释法测定桂枝茯苓丸对验证菌株的回收率,并对控制菌检查法进行验证。结果:桂枝茯苓丸对大肠埃希菌、白色念珠菌及黑曲霉菌无抑制作用;对金黄色葡萄球菌及枯草芽孢杆菌有较强抑制作用。结论:培养基稀释法适用于桂枝茯苓丸的微生物限度检查;常规平皿法适用于控制菌检查。
OBJECTIVE: To establish a method for the microbial limit test of Guizhi funing pills. METHODS: The recovery rates of tested strains treated by Guizhi funing pills were determined by plating method and medium dilution method. The test method of the control bacteria was verified. RESULTS: Guizhi funing pills had no inhibitory action on escherichia coli, canidia albicans and aspergillus niger, but which had potent bacteriostatic action on staphylococcus aureus and bacillus subtilis. CONCLUSION: The medium dilution method is suitable for microbial limit test of Guizhi funing pills, whereas the conventional plating method is applicable for the test of control bacteria.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第21期1656-1657,共2页
China Pharmacy
关键词
桂枝茯苓丸
微生物限度检查
抑菌
Guizhi ruling pills
Microbial limit test
Bacteriostasis