摘要
介绍了一套适用于小动物成像的高分辨微型CT成像系统。该系统采用用焦点为100μm的微焦点射线源和成像面积为13cm×13cm的平板探测器测量数据,以旋转扫描的锥束算法进行图像重建。经测试,平板探测器的MTF在调制度10%时,可达到31lp/cm;CT系统放大倍率为1.94时,分辨率可达185μm。用兔股骨为样品,可清晰观察到骨小梁结构,表明该系统可高分辨地实现小动物样本的三维结构成像。
A high resolution Micro-CT system for small animal imaging is introduced in this paper. Micro-focus X-ray tube with focal diameter of 100 μm and fiat panel detector with imaging area of 13cm × 13cm are adopted in this system. The data acquired in rotation scanning is reconstructed with cone beam algorithm. The resolving power of the detector is measured to be 31 lp/cm at 10% of the MTF. The resolution of the Micro-CT system could achieve 185 μm when the magnification factor is 1.94. Thighbone of a rabbit is used as sample imaging with the system. The trabecular bone could be imaged clearly. And the ability of small animal imaging of the system has been demonstrated.
出处
《中国医疗器械杂志》
CAS
2009年第4期255-258,共4页
Chinese Journal of Medical Instrumentation
基金
863重点项目资助(小动物活体光学分子成像装置2006AA020801)
关键词
微型CT
平板探测器
小动物成像
micro-CT, flat panel detector, small animal imaging
