摘要
目的:了解我院住院患者抗菌药物临床应用情况,为临床安全、合理、有效地使用抗菌药物提供参考。方法:对我院2008年住院患者抗菌药物应用品种、销售金额和用药频度(DDDs)等进行统计分析;对2008年我院572份出院病历抗菌药物的使用情况编制调查表进行统计分析。结果:抗菌药物销售金额占药品总销售金额比例为26.64%,品种数最多、销售金额最大的是头孢菌素类,销售金额占抗菌药总金额的一半以上,销售金额和DDDs排序第1位的均为头孢吡肟针,三级抗菌药物使用频率偏高。抗菌药物使用率为74.30%,二联以上抗菌药物使用率为63.76%,治疗用药病原学检测送检率为72.15%,预防性用药占44.23%。结论:我院住院患者抗菌药物使用率偏高,选用高档抗菌药物较多,预防用药不规范,应进一步加强抗菌药物监管,促进抗菌药物的合理应用。
OBJECTIVE:To review the clinical utilization of antibacterials in the inpatients of our hospital for clinical references of safe,rational and effective use of antibacterials.METHODS:The antibacterials used in the inpatients hospitalized in 2008 in our hospital were analyzed statistically in respect of the antibiotic varieties,consumption sum and DDDs etc.Meanwhile,the medical records of 572 inpatients that were discharged from our hospital in 2008 were analyzed statistically in respect of the utilization of the antibacterials by a questionnaire survey.RESULTS:The antibacterials used in our hospital represented 26.64% of the total in terms of consumption.Cephalosporins took the lead in terms of varieties and consumption sum,representing more than a half of total consumption sum of antibacterials.Cefepime injections took the lead in both consumption sum and DDDs.The application frequency of the third grade antibacterials was on the high side.74.30% of patients used antibacterials;63.76% used at least two kinds of antibacterials in combination;72.1% received etiological test in therapeutic medication;prophylactic medication occupied 44.23%.CONCLUSION:The proportion of the inpatients receiving antibacterials and the use of high grade antibiotics were all on the high side and the preventive medication was not standard;therefore,it is urgent to tighten control on the use of antibacterials to promote their rational use.
出处
《中国医院用药评价与分析》
2009年第7期502-505,共4页
Evaluation and Analysis of Drug-use in Hospitals of China