摘要
目的探讨急性丘脑卒中并发脑心综合征(BHS)的临床特征及发病机制。方法回顾性分析64例BHS患者的临床资料。结果急性丘脑卒中患者脑心综合征发生率为38.1%,其中76.6%的患者在急性丘脑卒中后72h内发病。心脏损害主要表现为心电图复极异常、心肌缺血或类心肌梗死、各类型心律失常,心肌酶谱升高,并且BHS随着病情的好转而好转,病死率为39.1%。结论急性丘脑卒中BHS发生率高,BHS的发生与丘脑卒中相关联,可能与丘脑受损导致自主神经中枢功能失调、心脏神经支配紊乱、神经-体液调节障碍等有关。
Objective To investigate the clinical characteristics and pathogenesis of brain-heart syndrome (BHS) in patients with acute thalamic stroke. Methods The clinical data of 64 cases of BHS in patients with thalamic stroke were reviewed and analyzed retrospectively. Results The incidence of BHS was 38.1% in thalamic stroke patients, and 76.6% of them were attacked with BHS within 72 hours after thalamic stroke onset. The main manifestations of myocardial injury were re-polarization abnormality,arrhythmia on ECG and increaseing in cardiac enzymes. As thalamic stroke was controlled, BHS was alleviatde gradually. The total death rate was 39.1%. Conclusion BHS causes high mortality rate in patients with thalamic stroke. The pathogenesis may be related to the disturbance of autonomic nervous center, cardiac innervation andneural - humoral regulation resulted from the injury of thalamus.
出处
《中国现代医生》
2009年第24期109-110,共2页
China Modern Doctor
关键词
急性丘脑卒中
脑心综合征
Acute thalamic stroke
Brain-heart syndrome