摘要
目的探讨低透析液流量血液透析方式对于预防透析失衡综合症的疗效。方法选择血液透析新患者共65例,随机分组为低透析液流量组和短时低效透析组,比较透析失衡发生率、尿素清除率和清除速率、血浆渗透压改变和改变速率。结果低透析液流量组透析失衡发生率与短时低效组差异无显著性(P>0.05),但尿素清除率高(P<0.05),尿素清除速率和血浆渗透压改变速率低(P<0.01)。结论低透析液流量预防透析失衡综合症的发生相比,短时低效透析效果相近或更好,同时能提高透析疗效,可能是一种有效预防透析失衡的治疗方式。
[Objective] To investigate the preventive effect of low dialysate flow to dialysis disequilibrium syndrome. [Methods] Sixty-five patients received hemodialysis for the first time were included. All of them were randomly divided into experimental group （low dialysate flow） and control group （short time and low efficiency）. The incidence rate of dialysis disequilibrium, the clearance rate and clearance rate speed of urea nitrogen, the volume change and volume change speed of osmotic pressure were analyzed and compared between the two groups. [Resuits] The occurrence of dialysis disequilibrium syndrome did not have significant difference between the two groups （P 〉0.05）. The urea nitrogen clearance rate in experimental group was higher than in control group （P 〈0.05）. The speeds of urea nitrogen clearance rate and osmotic pressure volume change in experimental group were lower in control group （P 〈0.01）. [Conclusion] The hemodialysis by low dialysate flow possesses higher efficiency than by method of short time and low efficiency. Maybe this method could effectively prevent the occurance of dialysis disequilibrium syndrome.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第15期2315-2317,共3页
China Journal of Modern Medicine
关键词
低透析液流量
血液透析
透析失衡综合症
low dialysate flow
hemodialysis
dialysis disequilibrium syndrome
