摘要
目的观察术前抗胆碱药物对全麻苏醒期导尿管不适的影响。方法择期手术男性患者300例,随机均分为三组:术前30min肌注盐酸戊乙奎醚0.01mg/kg组(P组)、阿托品0.01mg/kg组(A组)、不给抗胆碱药物为对照组(C组)。三组均在全麻后留置导尿管;苏醒期对导尿管不适严重程度评估。结果P组术后中度以上导尿管不适发生率明显低于A和C组(P<0.01)。结论术前给予盐酸戊乙奎醚可明显减轻全麻苏醒期的导尿管不适。
Objective To evaluate the effect of preoprative anticholinergic agents on the catheter-related bladder discomfort after general anaesthesia. Methods Three hundred male adult patients undergoing selective surgery were randomized into three groups with 100 cases each. Group A received atropine 0.01 mg/kg and group P received penehyclidine 0. 01 mg/kg im. 30 min before surgery. Group C was given no anticholinergic agents as the control. After anaesthesia induction, all patients were catheterized with a 12 Fr Foley＇ s catheter and the balloon was inflated with 8 ml distilled water. The bladder discomfort was assessed during recovery in the post-anaesthesia care unit. Severity of bladder discomfort was graded as mild, moderate and severe. Results Lower incidence of moderate and severe bladder discomfort was observed in group P compared with group A and group C （P〈0. 01） . Conclusion Preoprative penehyclidine 0. 01 mg/kg is effective in reducing the severity of the catheter-related bladder discomfort after general anaesthesia.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2009年第8期681-682,共2页
Journal of Clinical Anesthesiology
