摘要
目的通过对8例艾滋病合并新型隐球菌脑膜炎的临床特征及转归的分析,提高对艾滋病合并新型隐球菌脑膜炎的认识。方法对该院2004年9月～2009年2月收治的8例艾滋病合并新型隐球菌脑膜炎病例进行回顾性分析。结果8例新型隐球菌脑膜炎患者均为艾滋病晚期患者,在确诊时已合并多种机会感染,所有患者出现头痛,1例未经治疗死亡,1例自动出院,6例应用两性霉素B或两性霉素B脂质体抗真菌治疗后,4例病情好转,2例死亡。结论艾滋病患者合并新型隐球菌脑膜炎病情重,预后差,早发现早治疗,两性霉素B或两性霉素B脂质体治疗可取得较好的治疗效果。
[ Objective ] To increase the understanding of AIDS and Cryptococcus neoformans meningitis coinfection. [ Methods ] 8 cases of AIDS coinfected with C. neoformans meningitis admitted from September. 2004 to Feb. 2006 were retrospectively reviewed. [Results] Eight cases of cryptococcal meningitis in patients with advanced AIDS are at the time of diagnosis have been consolidated a variety of opportunistic infections. All patients Came with headache. One case of death had no treatment, one case gave up treatment, six eases of the applied of amphoteriein B or liposomal arnphoteriein B antifungal treatment, four of them improved,the other two patients died. [ Conclusions] The clinical condition is serious with poor outcome in AIDS patients coinfected with C. neoformans meningitis. To early infections, the early treatment of Amphoteriein B or liposomal will realize a better therapeutic effect.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第16期2485-2487,2490,共4页
China Journal of Modern Medicine
关键词
新型隐球菌脑膜炎
艾滋病
临床特征
转归
eryptoeoeeus neoformans meningitis
acquired immune deficiency syndrome
clinical feature
tulnover
