摘要
用Ｂａ１４ＣＯ３为原料，合成１４Ｃ氰化钠、硝酸胍和苄基磺酰胺等中间体，最终得到１４Ｃ苄嘧磺隆产品。放化收率为１４６％，放化纯度大于９５％，放射性比活度为０７８１μＣｉ／ｍｇ（２８８９７ｋＢｑ／ｍｇ）。
C 4 pyrimidinyl) bensulfuron methyl was synthesized from 14 C sodium cyanide with 6 steps. First, malonic acid ( 14 C carboxyl) was prepared, then changed to ethyl ( 14 C carboxyl) malonate by diazoethane. It reacted with guanidine nitrate, forming 14 C 2 amino 4,6 dihydroxy pyrimidine, which changed into 14 C 2 amino 4,6 dimethyloxy pyrimidine. This product reacted with methyl 2 (methylene sulfonyl isocyanate) benzoate, forming ( 14 C 4 pyrimidinyl) bensulfuron methyl. The radiochemical yield was 14 6%, radiochemical purity was more than 95%, and the specific activity was 28 9 kBq/mg.
出处
《核农学报》
CAS
CSCD
1998年第3期175-178,共4页
Journal of Nuclear Agricultural Sciences
关键词
除草剂
苄嘧磺隆
放射性
碳14
Herbicide, 14 C labeling, bensulfuron methyl
