摘要
目的:评价3种化疗方案治疗脊柱结核的经济学效果。方法:125例脊柱结核患者分成A、B、C组,均服用利福平、吡嗪酰胺、异烟肼和肌肉注射链霉素注射液,全程观察超短化疗4.5个月(A组)、短程化疗8个月(B组)、标准化疗12个月(C组)的疗效,记录不良反应,并进行药物经济学分析。结果:A、B、C组有效率分别为93.18%、92.50%、92.68%(P>0.05),成本分别为330.27、540.48、790.73元。结论:A组方案较佳。
OBJECTIVE： To evaluate the pharmacoeconomic efficacy of 3 therapeutic schemes in the treatment of spinal tuberculosis. METHODS： 125 patients with spinal tuberculosis were randomly divided into three groups： Group A（ultra-short course of chemotherapy of 4.5 months）, Group B（short course of chemotherapy of 8 months） and Group C（standard course of chemotherapy of 12 months） . All were treated with rifapicin, pyrazinamide, isoniazid and streptomycin injections concomitantly. The curative efficacy and adverse drug reactions throughout the treatment course were recorded and a cost- mini-mization analysis was performed. RESULTS： The effective rates of group A, B and C were 93.18%, 92.50% and 92.68%, respectively（ P 〉 0.05）, and the costs were 330.27 yuan, 540.48 yuan and 790.73 yuan, respectively. CONCLUSION ： Regime A was proved to be the optimal scheme.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第29期2244-2246,共3页
China Pharmacy
关键词
脊柱结核
利福平
吡嗪酰胺
异烟肼
链霉素
化疗方案
最小成本分析
Spinal tuberculosis
Rifapicin
Pyrazinamide
Isoniazid
Streptomycin
Chemotherapy
Cost- minimization analysis
