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三阴性乳腺癌的研究进展

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摘要 乳腺癌是一种异质性肿瘤，在组织形态、免疫表型、生物学行为及治疗反应上存在着极大的差异。2000年美国斯坦福大学Perou和Sorlie等首先采用cDNA微阵列技术对乳腺癌手术标本进行分析，根据基因表达谱的差异将乳腺癌分为5个亚型：Luminal A，Luminal B，Normal—like，HER-2阳性型及Basal-like型。不同的亚型对治疗的反应和预后存在显著差异。
作者 柴文英 程若川 蒋爱梅
机构地区 昆明医学院第一附属医院乳腺外科
出处 《云南医药》 CAS 2009年第5期598-603,共6页 Medicine and Pharmacy of Yunnan
关键词 三阴乳腺癌 病理 治疗 预后
分类号 R737.9 [医药卫生—肿瘤]
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参考文献38

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二级参考文献31

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云南医药
2009年 第5期

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