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变应原体外检测对咳嗽变异性哮喘的诊断意义 被引量:1

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摘要 目的了解应用变应原体外检测系统进行变应原筛查和血清嗜酸细胞阳离子蛋白(ECP)测定对咳嗽变异性哮喘诊断的意义。方法选择CVA患儿32例(CVA组)、支气管哮喘(CVA除外)患儿29例(支气管哮喘组)、肺炎患儿30例(肺炎组)、健康儿童22例(正常对照组),应用变应原体外检测系统进行变应原过筛试验及各组血清嗜酸细胞阳离子蛋白(ECP)水平测定。结果变应原过筛实验阳性率:CVA组75.0%,支气管哮喘组79.3%,肺炎组10.0%,正常对照组13.6%,CVA组与支气管哮喘组比较差异无统计学意义(P>0.05),而CVA组与肺炎组及正常对照组比较差异有统计学意义(P<0.01)。血清ECP水平:CVA组为(17.50±6.98)μg/L,支气管哮喘组为(16.55±3.56)μg/L,肺炎组为(5.62±3.66)μg/L,正常对照组为(4.18±2.14)μg/L,CVA组与支气管哮喘组比较差异无统计学意义(P>0.05),而CVA组与肺炎组及正常对照组比较差异有统计学意义(P<0.01)。结论变应原体外检测系统进行过敏原筛查试验及ECP测检对诊断咳嗽变异性哮喘有重要意义。
出处 《广东医学院学报》 2009年第4期446-447,共2页 Journal of Guangdong Medical College
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