摘要
目的探讨应用子宫内膜采集器进行子宫内膜细胞学检查的准确性。方法2008年1～5月,对193例在我院门诊需要进行子宫内膜检查的患者用子宫内膜采集器进行宫腔细胞学检查,并与诊断性刮宫组织学检查结果进行比较。结果193例中,内膜采集器标本合格率93.8%(181/193),诊刮标本合格率为99.0%(191/193)(χ2=7.412,P=0.006)。诊刮确诊为子宫内膜恶性病变13例,细胞学诊断子宫内膜恶性病变的敏感性和特异性分别为69.2%(9/13)及100.0%(166/166),准确率为97.8%(175/179);诊刮确诊为子宫内膜增生性病变18例,细胞学诊断子宫内膜增生性病变的敏感性及特异性分别为27.8%(5/18)及98.8%(159/161),准确率为91.6%(164/179);诊刮确诊为子宫内膜良性非增生性病变共10例,细胞学诊断的敏感性及特异性分别为60.0%(6/10)及98.8%(167/169),准确率为96.6%(173/179);80例取材满意的不孕症患者宫腔细胞学检查判断有无腺体分泌的准确率为100%。结论子宫内膜采集器宫腔细胞学检查对于诊断子宫内膜恶性病变及不孕症患者的子宫内膜检查有一定意义,但对于子宫内膜增生性病变及良性非增生性病变的诊断价值还需进一步探讨。
Objective To probe into the diagnostic accuracy of endometrial sampling device in the detection of endometrial lesions by cytology. Methods Endometrial cytological examination was performed on totally 193 out-patients from January to May 2008, the results were compared with the histological results by diagnostic curettage （D＆C）. Results The sampling qualified rate of endometrial sampling device was 93.8% （181/193） while that of D＆C was 99.0% （ 191/193, χ^2 = 7. 412, P = 0. 006）. Thirteen patients were diagnosed with endometrial malignant lesions by D＆C. In these patients, the sensitivity and specificity of cytology was 69.2% （9/13） and 100.0% （166/166）, respectively; and its accuracy rate was 97.8% （175/179）. By D＆C 18 patients were diagnosed with endometrial hyperplasia, in whom the sensitivity and specificity of cytology was 27. 8% （5/18） and 98. 8% （159/161）, respectively, and the accuracy rate was 91.6% （164/179）. Ten patients were confirmed as having endometrial benign lesions without hyperplasia by D＆C, for whom the sensitivity and specificity of cytology was 60.0% （6/10） and 98.8% （167/169） respectively, and the accuracy rate was 96.6% （173/179）. The accuracy rate of endometrial cytological examination for 80 infertility patients with satisfactory sample was 100% , when the main objective was to determine whether the endometrial gland secreted or not. Conclusion Cytological examination by endometrial sampling device is feasible in the detection of endometrial malignant lesions and inspection of endometrium for infertility patients, but further discussion is necessary in the detection of endometrial benign lesions.
出处
《中国微创外科杂志》
CSCD
2009年第10期869-872,共4页
Chinese Journal of Minimally Invasive Surgery
