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切除修复交叉互补基因1、生存素与顺铂耐药的研究进展 被引量：1

Research progress of excision repair cross-complementing 1, survivin and cisplatin resistance
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摘要 顺铂耐药有多种复杂机制参与，大量研究表明DNA修复途径的关键基因切除修复交叉互补。基因1和参与细胞凋亡和有丝分裂调控的生存素基因与顺铂耐药密切相关。 Cisplatin resistance is attributable to multiple intricate mechanisms. Many researches show that excision repair cross-complementing 1 which is the key gene of DNA repair pathways and survivin gene involved in apoptosis and mitosis regulation are closely related to cisplatin resistance.
作者 丁静 陈余清 李伟
机构地区 蚌埠医学院第一附属医院呼吸内科
出处 《国际呼吸杂志》 2009年第20期1269-1272,共4页 International Journal of Respiration
基金 安徽省自然科学基金资助项目（070413094）
关键词 切除修复交叉互补基因1 生存素 顺铂耐药 Excision repair cross-complementing 1 Survivin Cisplatin resistance
分类号 R730.5 [医药卫生—肿瘤]
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参考文献26

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二级参考文献24

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国际呼吸杂志
2009年 第20期

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