摘要
目的:探讨插植调强近距离放疗在复发宫颈癌中的价值。方法:25例盆腔复发宫颈癌患者行插植后装调强近距离放疗为实验组,选择同期行常规后装放疗的25例盆腔复发宫颈癌患者作为对照组,比较两组间的近期疗效及合并症。结果:实验组完全缓解20例,部分缓解5例,对照纽完全缓解10例,部分缓解7例,稳定4例,进展4例,差异有统计学意义(P=0.005)。实验组出现5例阴道直肠瘘,1例3级肠炎;对照组出现3例阴道直肠瘘,1例3级肠炎。结论:盆腔插植调强近距离放疗治疗复发宫颈癌近期疗效满意,优于常规近距离放疗,毒副反应可耐受。
Objective： To explore the value of implanted intensity-modulated brachytherapy for recurred cervical carcinoma. Methods： A total of 25 cases of recurred cervical carcinoma were enrolled into the trial group which were treated with pelvic implanted afterloading intensity-modulated brachytherapy. The other 25 patients with recurred cervical carcinoma treated with routine brachytherapy during the same period were enrolled into the control group. Results： There were 20 cases with CR and 5 cases with PR in the trial group, and 10 cases with CR, 7 cases with PR, 4 cases with SD and 4 cases with PD in the control group, with a significant difference between the two groups （P〈0.05）. In the trial group, there were 5 cases with vaginal-rectal fistula and 1 case with grade 3 enteritis. In the control group, there were 3 cases with vaginal-rectal fistula. Conclusion： Pelvic implanted intensity-modulated brachytherapy for recurred cervical carcinoma is satisfactory with better short-term efficacy than that of the routine brachytherapy and tolerable side effects.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2009年第21期1219-1222,共4页
Chinese Journal of Clinical Oncology
关键词
宫颈肿瘤
治疗
近距离放疗
调强放疗
Cervical neoplasms
Therapy
Brachytherapy
Intensity modulated radiotherapy
