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某院门诊抗菌药物合理应用分析

Rationality in the Outpatient Utilization of Antibacterials in a Hospital
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摘要 目的:了解某院门诊抗菌药物的使用情况,为监督和管理抗菌药物的合理使用提供依据。方法:随机抽取2009年3月门诊处方2 435张。对其中的抗菌药物处方逐一审核,对其使用种类、注射剂使用情况、各种类处方所占比例、使用是否对症、联合使用、使用方法是否合适等情况进行分析。结果:某院门诊处方中抗菌药物使用比例为19.06%,使用频率排序前5位的分别是第3代头孢菌素、大环内酯类、硝基咪唑类、第1代头孢菌素和氟喹诺酮类。注射剂处方64张,占总抽检处方数的2.6%,其中使用频率排序前3位的分别为:头孢唑肟钠粉针、甲硝唑注射液和哌拉西林/舒巴坦粉针。不对症和联合不当处方共109张,占总抽检处方数的4.41%。使用方法不当处方共18张,占总抽检处方的0.73%。结论:该院门诊抗菌药物使用基本合理,但还需要进一步监督与管理。 OBJECTIVE: To probe into the outpatient utilization situation of antibacterials in a hospital to provide references for supervising and managing rational use of antibacterials. METHODS: 2 435 outpatient prescriptions in March were randomly selected, with the antibacterial prescriptions examined one by one for analyses with regard to drug categories, the utilization of injections, proportion of each kind of prescriptions, whether the drug utilization was indicated for the symptoms, drug combination, the suitability of administration etc. RESULTS: 19.06% of the outpatient prescriptions prescribed antibacterials. The top 5 categories in terms of DDDs included the third generation cephalosporin, macrolides, nitroimidazoles, the first generation cephalosporin and quinolones. 64 prescriptions (2.6%) prescribed injections, of which, the top 3 in terms of DDDs were Ceftizoxime Sodium injections, rnetronidazole injections and piperacillin / sulbactam injections. 109(4.41%) prescriptions involved non- indicated drug use and irrational drug combinations. 18(0.73%) were inappropriate in administration. CONCLUSION: The outpatient utilization of antibacterials in the hospital is rational on the whole, but for which further supervision is needed.
作者 刘敏 李忠东
出处 《中国医院用药评价与分析》 2009年第11期828-830,共3页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 抗菌药物 合理用药 处方 Antibacterials Rational medication Prescription
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