摘要
目的:了解我院抗感染药致不良反应发生的特点与一般规律。方法:对我院2004～2008年收集到的抗感染药致176例ADR报告进行汇总分析。结果:引起ADR的抗感染药涉及10类31个品种。176例ADR中,21～40岁构成比最高,占44.32%;头孢菌素类引起的ADR居首位,其次为喹诺酮类;以静脉滴注给药途径引起的ADR最常见(占89.77%);ADR涉及的器官或系统主要为皮肤及其附件;绝大多数ADR转归良好。结论:抗感染药发生ADR与多种因素相关。临床在使用时应引起足够的重视,以减少ADR的发生。
Objective：To investigate the characteristics and regularities of adverse drug reactions（ADR） induced by anti-infective drugs in our hospital.Method：176 ADR cases induced by anti-infective drugs collected by the ADR monitoring center in our hospital from 2004 to 2008 were classified and analyzed.Result：10 categories（31 kinds） of anti-infective drugs were involved in all the ADR cases,of which,those patients aged above 21-40 years accounted for 44. 32%.The ADRs were chiefly induced by cephalosporins,followed by quinolones. Of the total 176 cases, 89.77% were induced by the intravenous route. The lesions of skin and its accessories were the predominant presentation of ADRs. And the majority of ADR cases had a good turnover. Conclusion： Multiple factors contributed to the ADR,to which great importance should be attached so as to reduce the incidence of ADR induced by anti- infectives.
出处
《药物流行病学杂志》
CAS
2009年第6期427-429,共3页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
抗感染药
Adverse drug reactions
Anti-infective Drugs
