摘要
目的:观察葛根素联合胺腆酮治疗对持续性心房颤动复律的作用。方法:有症状的持续性房颤87例,随机分为葛根素加胺碘酮组44例和单用胺碘酮组43例,治疗4周。观察房颤转复时间、成功率、QT间期及药物副作用。结果:葛根素加胺碘酮组平均复律时间显著缩短(7.5 d,10.2 d,P<0.01),房颤转复率显著高于单用胺碘酮组(77.3%,60.5%,P<0.01)。结论:葛根素辅助治疗可以缩短房颤转复时间,提高房颤转复成功率,无明显不良反应。
Objective：To compare the efficacy of oral cordarone and Puerarin in conversion of persistent atrial fibrillation and control of ventricular rates.Methods：The efficacy and safety of amiodarone and Puerarin add amiodarone were studied in 87patients with persistent atrial fibrillation.The amiodarone 200 mg tid×7 d,200 mg bid×7 d,200 mgqd×7 d or Puerarin 40 mL were given intravenonsly×21 d.The cardiac rhythms,ventricular rates,QT duration,BP and side effects of the drugs were observed during.Results：In 43 patients with paroxysreal artial fibrillation were conversed to sinus rhythm,44 patients of amiodarone and Puerarin group,34 out of 44 patients with paroxysmal atrial fibrillation were conversed to sinus rhythm. The ventricular rates were obviously controlled and QT duation had no significantr difference. The average conversion time of amiodarone group was 10. 2 days and that of amiod- arone and Pnerarin group was 7. 5 days. Conclusions：These data demonstrate that amiodrone and Puerarin is more effective than amiodrone in converting persistent atrial fibrillation and both drugs can effectively control the ventricular rates.
出处
《航空航天医药》
2009年第12期17-18,共2页
Aerospace Medicine
关键词
葛根素
房颤
复律
Puerarin
Atrial fibrillation
Convesion
