摘要
目的:了解杭州地区女性人乳头瘤病毒(HPV)各基因型感染的分布情况,为杭州地区HPV分子流行病学研究提供依据。方法:采用导流杂交技术,可同时检测21种HPV:其中15种高危型HPV,6种低危型HPV。结果:706例女性标本共检出阳性196例(27.8%),其中高危型HPV152例(21.5%,152/706,含多重感染),单一HPV亚型感染141例(20.0%,141/706),多重感染55例(7.8%,55/706);共检出20种亚型HPV,其中高危型HPV16种,低危型5种,HPV16、52、58、33、18、66、31、53是最常见的高危型。结论:开展各型HPV检测对于HPV感染的诊断、治疗及宫颈癌的早期干预和预防具有重要意义。
Objective：To report type-specific prevalence and distribution of human papillomavirus（HPV） in women who underwent cytologic screening in Hangzhou region.To supply basis for study on epidemiological.Methods：A total of 21 genotypes including 15 high-risk types and 6 low-risk types were tested by flow-through rapid hybridization.Results：Among the 706 women,HPV was detected in 196 women（27.8%,196/706）.The high-risk types were 152 cases（21.5%,152/706,including multiple infection）.The infection of single genotype was 141 cases（20.0%,141/706）and multiple infection was 55 cases（7.8%,55/706）.Total 20 genotypes were detected,including 15 high-risk and 5 low-risk types.HPV16,52,58,33,18,66,31 and 53 were the most prevalent high-risk types.Conclusion：The detection of human papillomavirus genotype is important for the women who underwent cytologic screening in early period diagnosis and prevention.
出处
《中国卫生检验杂志》
CAS
2009年第12期2896-2897,共2页
Chinese Journal of Health Laboratory Technology
