摘要
目的:探讨芬必得超前镇痛效果以及超前镇痛在玻璃体切除术中的临床意义。方法:将60例玻璃体切除术的受术者,随机分为芬必得组和葡萄糖酸钙组,分别在术前口服芬必得或葡萄糖酸钙,局部麻醉下行玻璃体切除术,采用11点数字评分法(the11-point numeric rating scale,NRS-11)观测做巩膜切口、眼内操作及结束时受术者的疼痛程度并记录分析,手术结束后统计受术者对手术过程的总体满意度;观察术后3d两组房水闪光情况。结果:巩膜切口、眼内操作及结束时芬必得组NRS-11评分均低于葡萄糖酸钙组,差异有显著意义(P<0.01);术后3d两组房水闪光情况比较,差异有显著意义(P<0.05);两组的不良反应发生率差异无统计学意义。结论:术前口服芬必得明显减轻巩膜切口、眼内操作及结束时疼痛,非甾体类抗炎药芬必得用于玻璃体切除术受术者时,能够明显减轻手术疼痛,提高其对手术效果的满意度。
AIM： To observe the effect of the preemptive analgesia with ibuprofen sustained-release capsules for vitrectomy. METHODS： Sixty patients were randomly assigned into two groups who received single oral dose of ibuprofen sustained-release capsules or calcium gluconate, respectively before the operation. The degrees of pain were evaluated by the 11-point numeric rating scale（NRS-11） at the beginning and the end of the operation. Adverse effects and the overall satisfaction on analgesic therapy were assessed when operation was finished. The extent of aqueous flare in the third day after operations was observed.RESULTS： The NRS-11 scores of the experimental group were significantly lower than those of the control group at the beginning and the end of operation （P〈0.01） . There were no significant differences between the two groups in side effects.CONCLUSION. Ibuprofen sustained-release capsules could produce preemptive effect. Preoperative oral administration of ibuprofen sustained-release capsules may provide patients with good analgesia in operation.
出处
《国际眼科杂志》
CAS
2009年第12期2430-2431,共2页
International Eye Science
关键词
芬必得
超前镇痛
玻璃体切除术
ibuprofen sustained-release capsules
preemptive analgesia
vitrectomy
