摘要
近年来,国内外学者关注于肝纤维化的无创性诊断.其中,多种血清纤维化指标检验及影像学检查是目前临床较为常用的无创性评估肝纤维化的方法,但敏感性和特异性不高.Fibroscan是一种对肝纤维化进行定量诊断的新技术,以瞬时弹性成像为原理,通过对肝脏硬度指标的测量进行肝纤维化程度评估.本文就其工作原理、临界值确定、诊断价值及应用现状进行综述.
In recent years, non-invasive methods for assessment of liver fibrosis have attracted worldwide attention. However, although many biochemical markers and imaging examinations have been used for evaluation of liver fibrosis, their sensitivity and specificity are low. Fibroscan (transient elastography) is a new non-invasive technology to assess the degree of liver fibrosis by measuring liver stiffness. Although Fibroscan has been extensively used to evaluate chronic hepatitis C and its complications in other countries, its use is uncommon in China. In this article, we will review its working principle, diagnostic value, and application status.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第31期3223-3228,共6页
World Chinese Journal of Digestology