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Fibroscan对肝纤维化诊断价值的研究进展 被引量:31

Recent advances in the use of Fibroscan for diagnosis of liver fibrosis
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摘要 近年来,国内外学者关注于肝纤维化的无创性诊断.其中,多种血清纤维化指标检验及影像学检查是目前临床较为常用的无创性评估肝纤维化的方法,但敏感性和特异性不高.Fibroscan是一种对肝纤维化进行定量诊断的新技术,以瞬时弹性成像为原理,通过对肝脏硬度指标的测量进行肝纤维化程度评估.本文就其工作原理、临界值确定、诊断价值及应用现状进行综述. In recent years, non-invasive methods for assessment of liver fibrosis have attracted worldwide attention. However, although many biochemical markers and imaging examinations have been used for evaluation of liver fibrosis, their sensitivity and specificity are low. Fibroscan (transient elastography) is a new non-invasive technology to assess the degree of liver fibrosis by measuring liver stiffness. Although Fibroscan has been extensively used to evaluate chronic hepatitis C and its complications in other countries, its use is uncommon in China. In this article, we will review its working principle, diagnostic value, and application status.
出处 《世界华人消化杂志》 CAS 北大核心 2009年第31期3223-3228,共6页 World Chinese Journal of Digestology
关键词 FIBROSCAN 肝纤维化 诊断价值 Fibroscan Liver fibrosis Diagnostic value
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参考文献61

  • 1Modig J, Busch C, Waernbaum G. Effects of graded infusions of monomethylmethacrylate on coagulation, blood lipids, respiration and circulation. An experimental study in dogs. Clin Orthop Relat Res 1975; : 187-197.
  • 2Wong GL, Wong VW, Choi PC, Chan AW, Chum RH, Chan HK, Lau KK, Chim AM, Yiu KK, Chart FK, Sung JJ, Chan HL. Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases. Clin Gastroenterol Hepatol 2008; 6:1027-1035.
  • 3Poynard T, Morra R, Ingiliz P, Imbert-Bismut F, Thabut D, Messous D, Munteanu M, Massard J, Benhamou Y, Ratziu V. Assessment of liver fibrosis: noninvasive means. Saudi J Gastroenterol 2008; 14: 163-173.
  • 4Castera L, Le Bail B, Roudot-Thoraval F, Bernard PH, Foucher J, Merrouche W, Couzigou P, de Ledinghen V. Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores. J Hepatol 2009; 50: 59-68.
  • 5Sanchez-Conde M, Montes-Ramirez ML, Miralles P, Castro Alvarez JM, Bellon JM, Ramirez M, Arribas JR, Gutierrez I, Lopez JC, Cosin J, Alvarez E, Gonzalez J, Berenguer J. Comparison of transient elastography and liver biopsy for the assessment of liver fibrosis in HIV/hepatitis C virus-coinfected patients and correlation with noninvasive serum markers. J Viral Hepat 2009 Sep 2. [Epub ahead of print].
  • 6Sandrin L, Fourquet B, Hasquenoph JM, Yon S, Fournier C, Mal F, Christidis C, Ziol M, Poulet B, Kazemi F, Beaugrand M, Palau R. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol 2003; 29:1705-1713.
  • 7Vergniol J, de Ledinghen V. [Transient elastography (FibroScan): a new tool in hepatology] Presse Med 2009; 38:1516-1525.
  • 8王宇,贾继东.Fibroscan评价肝纤维化进程[J].肝脏,2007,12(5):336-338. 被引量:29
  • 9Poynard T, Halfon P, Castera L, Munteanu M, Imbert-Bismut F, Ratziu V. Benhamou Y, Bourliere M, de Ledinghen V. Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Clin Chem 2007; 53:1615-1622.
  • 10Takemoto R, Nakamuta M, Aoyagi Y, Fujino T, Yasutake K, Koga K, Yoshimoto T, Miyahara T, Fukuizumi K, Wada Y, Takami Y, Saitsu H, Harada N, Nakashima M, Enjoji M. Validity of FibroScan values for predicting hepatic fibrosis stage in patients with chronic HCV infection. J Dig Dis 2009; 10:145-148.

二级参考文献57

  • 1尹珊珊,王宝恩,王泰龄,贾继东,钱林学.复方861治疗慢性乙型肝炎肝纤维化与早期肝硬化的临床研究[J].中华肝脏病杂志,2004,12(8):467-470. 被引量:81
  • 2Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association.肝衰竭诊疗指南[J].中华肝脏病杂志,2006,14(9):643-646. 被引量:831
  • 3王介非,廖粤斌,钱志平,巫善明.终末期肝病模型评分的临床应用[J].肝脏,2006,11(5):365-366. 被引量:2
  • 4Bravo AA, Sheth SG, Chopra S. Liver biopsy. N Engl J Med, 2001, 344: 495-500.
  • 5Bedossa P, Dargere D, Paradis V, et al. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology, 2003, 38: 1449-1457.
  • 6Chen Y, Wang BE, Jia JD, et al. Noninvasive evaluation of liver fibrosis in chronic hepatitis B patients. Zhonghua Gan Zang Bing Za Zhi, 2003, 11:354 -357.
  • 7Sandrin I., Fourquet B, Hasquenoph JM, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol, 2003, 29: 1705-1713.
  • 8Talwalkar JA, Kurtz DM, Schoenleber SJ, et al. Ultrasound- based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis. Clin Gastroenterol Hepatol, 2007, 5: 1214-1220.
  • 9Ziol M, Handra l.uca A, Kettaneh A, et al. Noninvasive assessrnent of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology, 20(15, 41 : 48-54.
  • 10Bonacini M, Hadi G, Govindarajan S, et al. Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol, 1997, 92:1302- 1304.

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