摘要
１８８６年英国ＬａｎｇＤｏｗｎ首先对此病作了描述。此病因严重智力发育迟缓，肌张力低下，小头畸形，宽眼距等而引起临床上关注，称唐氏综合征（Ｄｏｗｎｓｙｎｄｏｍｅ，Ｄｓ）。作为２１三体染色体疾病，首先是法国儿科医生Ｌｅｊｅｕｎｅ于１９５９年证实的。Ｄｓ是...
The aim of maternal serum screening (MSS) is to define patients at inscreased risk for Down's syndrome (Ds). During past ten years, the western researchers of prenatal diagnosis for Ds have done a lot of valuable work. In 1996 International Prenatal Screening Group's study gave conclusion: The performance of screening using maternal age and serum free bate hCG and PAPP A at ten weeks of pregnancies was better combination of MSS. It's early enough for the pregnancy woman given positive result to be performed further diagnosis by CVS or Ac. MSS is helpful to prenatal diagnosis for Ds has been demonstrated by many laboratories. Some researchers in asian countries or areas have made prospective studies on MSS for fetal Ds. Because most pregnanceny women don't understand the meaning of 'increased risk'. It's necessary to make it clear to them and offer genetics consultant in time.
出处
《中国优生与遗传杂志》
1998年第4期1-4,共4页
Chinese Journal of Birth Health & Heredity
关键词
唐氏综合征
产前血清筛查
血清因子
母血
Prenatal screening, Down's syndrome, Maternal serum, Review.
