摘要
目的评价国产阿霉素联合化疗治疗骨转移肿瘤的效果。方法经病理确诊的恶性肿瘤并经有关检查证实有骨转移60例，随机分为两组。治疗组30例，采用阿霉素（ADM）联合化疗方案；对照组30例，采用非ADM联合化疗方案，21天为一周期，连续用3～4个周期，观察指标包括临床症状和体征，X线片、ECT检查。随访时间4个月～12个月以上。结果治疗组与对照组的总有效率分别为56．7％和33．3％（P＜0．05）。结论国产ADM联合化疗方案可做为骨转移肿瘤的姑息性治疗方案。
To evaluate the therapeutic effect of ADM combination chemotherapy in the treatment of patientswith metastatic tumors of bone. METHODS A randomized clinical trial of ADM combination chemotherapy versusnon-ADM combination chemotherapy was carried out in 30 patients with metastatitc bone tumor, verified bypathology were treated with 3～4 cycles at 21 days intervals,the other 30 patients with 3～4 cycles of no ADMcombination chemotherapy at 21 days intervals. The observation criteria were clinical symptoms, physical signs,radioscopy and ECT scan changes,the follow up time was from 4 to 12 months. RESULTS The efficacy in theADM group was better, than the non-ADM group,responses being 56. 7% and 33. 3 % (PM<O. 05). CONCLUSIONADM chemotherapy can be considered to be a palliative chemotherapy regimen for metastatic tumors of bone.
出处
《中国癌症杂志》
CAS
CSCD
1998年第3期202-204,共3页
China Oncology
