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251例药品不良反应报告分析

Analysis of 251 cases of adverse drug reactions reports in our hosipital
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摘要 目的:了解药品不良反应(ADR)发生的特点及规律,为临床合理用药提供参考。方法:收集我院2008年1月~2009年4月上报的251例ADR报表,按性别、年龄、给药途径、药品品种、ADR累及器官或系统及临床表现、ADR程度等进行统计分析。结果:ADR发生率中,50岁以上患者较高,占49.01%;抗感染药物引起的最高,占50.55%。ADR主要临床表现为皮肤及其附件损害,共122例,占48.61%。结论:医院应重视并做好ADR的监测、分析、评价工作,以保证药物治疗安全有效。 Objective: To investigate and to analyze the occurrence and the characteristics of adverse reactions of drugs in our hospital and to provide references for the rational use of drugs in the clinic. Methods: 251 cases of ADR reports collected from January 2008 to April 2009 in our hospital were analyzed statistically in terms of patients' sex, age distribution, route of administration, drug varieties and ADR-involving organs/systems and clinical manifestations etc. Results: Patients over the age of 50 years shouted a higher incidence of ADR (49.01%), the anti-infective drugs showed the highest incidence rate of ADR (50.55%). The most common cilinical manifestations of ADR were the damage of skin and adnexa, 122 cases (48.61%). Conclusion: The hospitals should pay attention to the ADR monitoring, analysis, evaluation, and make sure the drug treatment is safe and effective.
作者 李悦 陈波
出处 《中国医药导报》 CAS 2010年第1期135-137,共3页 China Medical Herald
关键词 药品不良应 报告 统计 分析 Adverse drug reactions Reports Statistics Analysis
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