期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

抗环瓜氨酸肽抗体检测对老年人关节疼痛病因诊断的临床意义 被引量：1

原文传递
导出
摘要 类风湿关节炎（RA）是老年人常见病因之一，该病致残率高，患者生活质量低，预后差；但早期发现、早期治疗可显著改善预后。抗环瓜氨酸肽（CCP）抗体对于老年起病RA诊断的灵敏度与特异性良好，然而抗CCP抗体是否能取代传统的类风湿因子（RF），成为老年人RA的辅助检查。我们对100例60岁以上、以关节疼痛为首诊的老年患者血清分别进行RF和抗CCP抗体定量分析，以了解抗CCP抗体检测对老年人关节疼痛病因诊断及预测RA的价值。
作者 杨艳英 王宏智 吴美娟
机构地区 浙江省嘉兴市第一医院风湿免疫科
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2010年第1期49-50,共2页 Chinese Journal of Geriatrics
关键词 抗环瓜氨酸肽 病因诊断 关节疼痛 抗体检测 老年人 临床意义 抗CCP抗体 类风湿关节炎
分类号 R593.22 [医药卫生—内科学] R441.7 [医药卫生—诊断学]
  • 相关文献

参考文献6

  • 1Yazici Y, Paget SA. Elderly-onset rheumatoid arthritis. Rheum Dis Clin North Am, 2000, 26: 517-526.
  • 2魏锦,袁国华,黄慈波,周京国,唐中,蔚芃,杨明辉.老年类风湿关节炎患者43例临床分析[J].中华老年医学杂志,2004,23(1):27-29. 被引量：30
  • 3Lopez Hoyos M, Ruiz de Alegria C, Blanco R, et al. Clinical utility of anti CCP antibodies in the differential diagnosis of elderly onset rheumatoid arthritis and polymyalgia rheumatica. Rheumatology, 2004,43:655-657.
  • 4吴敏,谢雯,马英淳.抗环瓜氨酸肽抗体检测对老年人类风湿关节炎早期诊断价值的探讨[J].实用临床医学（江西）,2005,6(3):4-6. 被引量：7
  • 5Fong S,Chen PP, Fox RI, et al. Rheumatoid factors in human autoimmune disease: their origin, development and function. Pathol Immunopathol Res, 1986,5:305-316.
  • 6Palosuo T, Tilvis R, Strandberg T, et al. Filaggrin related antibodies among the aged. Ann Rheum Dis, 2003,62:261-263.

二级参考文献10

  • 1周彬,朱静,刘建,龙武彬,吴晓丹,程佳,吴侗.抗环瓜氨酸肽抗体检测在类风湿关节炎中的诊断及预后意义探讨[J].中华风湿病学杂志,2004,8(6):360-362. 被引量：51
  • 2Bajocchi G,La Corte R,Locaputo A,et al.Elderly onset rheumatoid arthritis:clinical aspects[J].Clin Exp Rheumatol, 2000,18(4):49～50.
  • 3Arnett FC,Edworthy SM,Bloch DA,et al.The american rheumatism association 1978 revised criteria for the classification of rheumatoid arthritis[J].Arthritis Rheum,1988,31(3):315～324.
  • 4Palosuo T,Tilvis R,Strandberg T,et al.Filaggrin related antibodies among the aged[J].Annals of the Rheumatic Diseases,2003,62(3):261～263.
  • 5Schellekens GA,Visser H,De Jong BAW,et al.The diagnostic properties of rheumatoid arthritis recognizing a cyclic citrullinated peptide[J]. Arthritis Rheum,2000,43(1):155～163.
  • 6Bas S, Perneger TV,Seitz M,et al.Diagnostic tests for rheumatoid arthritis:comparison of anti-cycliccitrullinated peptide antibodies,anti-keratin antibodies and IgM rheumatoid factors[J].Rheumatology,2002,41(7):809～814.
  • 7Lopez Hoyos M,Ruiz De Alegria C,Blanco R,et al.Clinical utility of anti-CCP antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica[J].Rheumatology,2004,43(5):655～657.
  • 8施桂英,袁国华.老年类风湿关节炎[J].风湿病学杂志,1997,2(3):3-5. 被引量：29
  • 9曾小峰,艾脉兴,甘晓丹,史艳萍,宋琴芳,唐福林.抗环瓜氨酸肽抗体检测在类风湿关节炎中的意义[J].中华风湿病学杂志,2001,5(5):281-284. 被引量：290
  • 10程秀峰,金琰,谭魁麟,谭军.老年类风湿关节炎患者抗角蛋白抗体检测意义[J].实用老年医学,2003,17(1):35-37. 被引量：8

共引文献34

同被引文献17

  • 1Li R, Sun J, Ren LM, et al. Epidemiology of eight common rheumatic diseases in China: a large-scale cross-sectional survey in Beijing[J]. Rheumatology (Oxford), 2012, 51:721-729.
  • 2Spinel-Bejarano N, Quintana G, Heredia R, et al. Comparative study of elderly-onset rheumatoid arthritis and young-onset rheumatoid arthritis in a Colombian population: clinical, laboratory and HLA- DRB1 findings[J]. Clin Exp Rheumatol, 2013, 31: 40-46.
  • 3Zintzaras E, Papathanasiou A, Ziogas D, et al. The reporting quality of studies investigating the diagnostic accuracy of anti-CCP antibody in rheumatoid arthritis and its impact on diagnostic estimates[J]. BMC Musculoskelet Disord, 2012, 13 : 113.
  • 4Aletaha D, Neogi T, Silman AJ, et al. 2010 rheumatoid arthritis classification criteria : an American College of Rheumatology/European League Against Rheumatism Collaborative Initiative[J]. Ann Rheum Dis, 2010, 69:1580-1588.
  • 5Stuhlmuller B, Ungethum U, Scholze S, et al. Identification of known and novel genes in activated monoeytes from patients with rheumatoid arthritis [J]. Arthritis Rheum, 2000, 43: 775-790.
  • 6Ohyama K, Kawakami A, Tamai M, et al. Serum immune complex containing thrombospondin-1: a novel biomarker for early rheumatoid arthritis[J]. Ann Rheum Dis, 2012, 71:1916-1917.
  • 7Wang JG, Xu WD, Zhai WT, et al. Disorders in angiogenesis and redox pathways are main factors contributing to the progression of rheumatoid arthritis: a comparative proteomics study [J] . Arthritis Rheum, 2012, 64:993-1004.
  • 8Rico MC, Castaneda JL, Manns JM, et al. Amelioration of inflammation, angiogenesis and CTGF expression in an arthritis model by a TSPl-derived peptide treatment[J]. J Cell Physiol, 2007, 211:504-512.
  • 9Manns JM, Uknis AB, Rico MC, et al. A peptide from thrombospondin 1 modulates experimental erosive arthritis by regulating connective tissue growth factor [J]. Arthritis Rheum, 2006, 54: 2415-2422.
  • 10Jou IM, Shiau AL, Chen SY, et al. Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis[J].Arthritis Rheum, 2005, 52: 339-344.

引证文献1

二级引证文献14

中华老年医学杂志
2010年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部