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联合检测PCT CRP对PPROM患者绒毛膜羊膜炎及潜伏期的临床诊断 被引量:4

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摘要 目的:探讨联合检测未足月胎膜早破(PPROM)孕妇血清降钙素原(PCT)及C反应蛋白(CRP)水平对绒毛膜羊膜炎及潜伏期长短的预测价值。方法:选取PPROM患者70例,相同孕周健康孕妇50例,检测血清PCT、CRP,记录患者自胎膜破裂至分娩发动的时间,PPROM患者分娩后,常规行胎盘胎膜病理检查。结果:PPROM组孕妇血清中PCT、CRP阳性率均高于相应对照组,差异有显著性(P<0.05)。PCT和CRP阳性诊断PPROM患者组织学绒毛膜羊膜炎的敏感性、特异性及阳性预测值、阴性预测值分别为62.22%、43.75%、60.87%、29.17%和57.78%、54.29%、67.86%、32.14%。两者同时阳性诊断绒毛膜羊膜炎的敏感性、特异性及阳性预测值、阴性预测值分别为66.67%、96%、96.77%、61.54%。两者同时阳性者潜伏期为4.23±1.87d,其他患者潜伏期为6.78±1.84d,两者比较差异有显著性(P<0.05)。结论:同时检测血清中PCT、CRP浓度,可大大提高对PPROM孕妇合并绒毛膜羊膜炎诊断的特异性和阳性预测价值并可预测潜伏期的长短。
出处 《河北医学》 CAS 2010年第1期31-33,共3页 Hebei Medicine
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参考文献3

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二级参考文献4

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共引文献4

同被引文献29

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