摘要
目的:从临床的角度观察、探讨丹参川芎嗪在治疗肾病综合症患者的临床意义。方法:临床随机选择24例原发性肾病综合症患者在传统激素、免疫抑制剂治疗基础上,加用丹参川芎嗪治疗,与对照组比较,观察其尿蛋白、尿量、血浆白蛋白、尿素氮、血肌酐等的变化。结果:24例丹参川芎嗪治疗组追踪观察8周,与对照组相比在治疗过程中尿蛋白明显下降,尿蛋白转阴疗程缩短,血浆白蛋白回升在治疗第4周后有明显统计学意义(p<0.01),两组治疗后比较血甘油三脂、胆固醇恢复正常无统计学意义。结论:丹参川芎嗪与激素联合治疗肾病综合征可起到协同积极的作用,值得临床借鉴。
Objective ： To observe and discuss the clinical significance of salviae miltiorrhizae and ligustrazine in treatment of nephritic syndrome in the clinical perspective. Methods： Randomly select 24 patients with idiopathic nephritic syndrome. On the basis of adopting traditional hormone and immunosuppress^ve agent treatment, add salviae miltiorrbizae and ligustrazine for treatment. Then compare with the control group, observe the changes of proteinuna, urine volume, plasma albumin, urea nitrogen, and serum creatinine etc. Results： After 8 weeks＇ follow-up observation of the 24 patients being treated with salviae miltiorrhizae and ligustrazine, it is found that their proteinuria significantly decreases during treatment compared with the control group, the treatment period of proteinuria becoming negative shortens, the recovery of plasma albumin level has obvious statistical significance after 4 weeks＇ treatment （/9〈0.01）; and after giving treatment to the two groups, their blood triglyceride and cholesterol become normal, which shows no statistical significance. Conclusion： Combined with hormone, salviae miltiorrhizae and ligustrazine has an active effect on treatment of nephritic syndrome, which can be used as clinical reference.
出处
《中国医药导刊》
2010年第1期41-41,43,共2页
Chinese Journal of Medicinal Guide
关键词
丹参川芎嗪
肾病综合症
治疗
Salviae Miltiorrhizae and Ligustrazine
Nephritic Syndrome：Treatment
