摘要
目的探讨绝经后妇女脆性骨折部位与骨密度(BMD)的关系。方法回顾性研究740例有脆性骨折的绝经后妇女,分析骨折部位和次数与BMD关系,应用双能X线吸收仪检测腰椎1～4和股骨近端BMD值。结果740例患者中,共发生838次骨折,椎体骨折、髋部骨折、桡骨远端骨折和外周骨折分别为192次(22.9%)、53次(6.3%)、159次(19.0%)和434次(51.8%),骨质疏松检出率分别为75.0%、81.1%、57.9%和49.1%,不同部位骨折处骨质疏松检出率间差异有统计学意义(P<0.01)。同时,多次骨折组的年龄显著高于一次骨折组(P<0.05),而其腰椎1～4、大转子(Troch)部位的BMD则显著低于一次骨折组(P<0.05)。结论绝经后妇女脆性骨折以椎体、桡骨远端为常见,髋部骨折较少见;发生髋部骨折者常具有低BMD;多次骨折患者年龄为危险因子。
Objective To analyze the association of fragility fracture site with bone mineral density（BMD）in postmenopausal women.Methods Totally 740 postmenopausal women with fragility fractures were retrospectively analyzed.BMD at the lumbar vertebrae 1-4（L1-4）and proximal femur were measures by dual energy X-ray absorptiometry.Results The number of fractures is 838 occurred in 740 women.The cases of vertebral compression fracture,hip fracture,distal radius fracture and other peripheral fractures are 192（22.9%）,53（6.3%）,159（19.0%）and 434（51.8%）respectively,and their rates of diagnosed osteoporosis are 75.0%,81.1%,57.9% and 49.1% respectively.The Age of those who suffered from more than one fracture is higher than that of those who had only one facture（P0.05）.But the BMD of L1-4 and greater trochanter is significantly lower in the former than in the latter（P0.05）.Conclusion Vertebral compression and distal radius fracture are common in postmenopausal women,nevertheless hip fracture takes place less.The hip fracture patients always have a lower BMD.Increasing of age is the risk factor of incidences of the fracture.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第4期372-373,376,共3页
Chinese General Practice
基金
国家自然科学基金资助项目(30771019,30570819,30800387)
上海市优秀学科带头人计划(08XD1403000)
关键词
骨质疏松
骨密度脆性骨折
绝经后妇女
Osteoporosis
Bone mineral density
Fragility fracture
Postmenopausal women
