摘要
目的:探讨肿瘤特异性生长因子(TSGF)在急性白血病中的表达和临床意义。方法:采用单克隆抗体透射比浊法测定62例急性白血病患者血清中TSGF水平。结果:急性白血病初诊患者血清TSGF水平明显低于正常对照组(P<0.01),完全缓解期TSGF水平恢复正常,未缓解和复发患者TSGF水平与初诊患者无明显差异(P>0.05)。结论:检测TSGF水平变化有助于急性白血病病情判断,可作为疗效观察的辅助指标。
Objective :To investigate clinical significance of tumor specific growth factor(TSGF) in patients with acute leukemia. Methods: Serum levels of TSGF in 68 patients with acute leukemia were determined by monoclonal antibody turbidimetry. Results : The serum level of TSGF in initial patients with acute leukemia was significantly high- er than that of control ( P 〈 0.01 ), and decreased to normal in the patients at complete remission period. There was no difference in TSGF between nonremission and relapse and initial patients (P 〉 0.05 ). Conclusion: Serum level of TSGF in the patients with acute leukemia is useful marker to judge state of illness, and TSGF may be regarded as assistant index of curative effect.
出处
《现代肿瘤医学》
CAS
2010年第3期550-551,共2页
Journal of Modern Oncology