摘要
单核细胞增生性李斯特菌(Listeria monocytogenes,LM)是重要的食源性人兽共患病原菌,LM的致病性与毒力因子密切相关,研究其毒力因子对于充分了解李斯特菌病的致病机制及有效防制该病有重要意义。作者对LM的毒力因子(如李斯特溶血素、肌动蛋白聚合蛋白、C型磷脂酶、内化素、细胞壁水解酶、酰胺酶及毒力调节因子如转录活化因子和应答调控因子等)和致病机理进行了综述。
Listeria monocytogenes（LM） is an important food-borne pathogen for animal and human＇s listeriosis.The pathogenicity of LM is closely correlated with virulence factors.Studying the virulence factors has important meaning to understand the pathogenic mechanism thoroughly and to prevent and cure listeriosis efficiently.The article reviewed the virulence factors（LLO,ActA,PLC,Inl,p60,Ami,PrfA,VirR,and so on）and the pathogenic mechanism of LM.
出处
《中国畜牧兽医》
CAS
北大核心
2010年第1期128-133,共6页
China Animal Husbandry & Veterinary Medicine
