摘要
卵巢恶性肿瘤的发病率近40年来增加了2~3倍并有逐步上升的趋势,根据美国癌症协会2007年的报道,22430例新诊断的卵巢癌病例中约有15280例死亡。约90%的卵巢恶性肿瘤为上皮性卵巢癌,其死亡率仍高居妇科恶性肿瘤死亡率之首,并位于妇女死亡原因第五位,严重威胁着妇女的生命和健康。
出处
《中国医药生物技术》
CSCD
2010年第1期53-56,共4页
Chinese Medicinal Biotechnology
基金
国家自然科学基金(30772320)
参考文献25
-
1Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2007. CA Cancer J Clin, 2007, 57(1):43-66.
-
2Herrin VE, Achtar MS, Steinberg SM, et al. A randomized phase Ⅱ p53 vaccine trial comparing subcutaneous direct administration with intravenous peptide-pulsed dendritic cells in high risk ovarian cancer patients//ASCO Annual Meeting, Chicago, 2007. Alexandria, USA: Journal of Clinical Oncology, 2007, 25(18):3011.
-
3Leffers N, Lambeck AJ, Gooden MJ, et al. Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase Ⅱ trial. Int J Cance, 2009, 125(9):2104-2113.
-
4Koido S, Nikrui N, Ohana M, et al. Assessment of fusion cells from patient-derived ovarian carcinoma cells and dendritic cells as a vaccine for clinical use. Gynecol Oncol, 2005, 99(2):462-471.
-
5Reinartz S, Kohler S, Schlebusch H, et al. Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (phase Ⅰb/Ⅱ). Clin Cancer Res, 2004, 10(5):1580-1587.
-
6Pfisterer J, du Bois A, Sehouli J, et al. The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A phase Ⅰ trial of the AGO-OVAR. Ann Oncol, 2006, 17(10):1568-1577.
-
7Datamonitor's business. Monoclonal Antibodies Update DMHC2427. (2008-06-06)[2009-05-02]. http://www.market-research-report.com/ datamonitor/DMHC2427.htm.
-
8Method MW, Gordon AN, Finkler N, et al. Final Analysis of a Randomized Dosing Study of oregovomab in Patients With Advanced Ovarian Cancer//ASCO Annual Meeting, Orlando, 2005. Alexandria, USA: Journal of Clinical Oncology, 2005, 23(16):5035.
-
9Berek JS, Taylor PT, Nicodemus CE CA125 velocity at relapse is a highly significant predictor of survival post relapse: results of a 5-year follow-up survey to a randomized placebo-controlled study of maintenance oregovomab immunotherapy in advanced ovarian cancer. J Immunother, 2008, 31(2):207-214.
-
10Berek J, Taylor P, McGuire W, et al. Oregovomab maintenance monoimmunotherapy does not improve outcomes in advanced ovarian cancer. J Clin Oncol, 2009, 27(3):418-425.
二级参考文献12
-
1施明,张冰,汤紫荣,雷周云,王慧芬,冯永毅,刘敬超,范振平,李捍卫,牟劲松,王福生.肝癌患者自体细胞因子诱导杀伤细胞治疗后免疫活性细胞的检测及其临床意义[J].中华医学杂志,2003,83(23):2049-2053. 被引量:37
-
2杨薇,陈敏华.射频消融治疗肝肿瘤疗效及其影响因素[J].中华医学杂志,2005,85(5):354-357. 被引量:13
-
3孟凡东,隋承光,王晓华,王扬,蒋涛,付立业,姜又红.卵巢癌患者自体细胞因子诱导杀伤细胞治疗前后免疫功能的检测与分析[J].中国实用妇科与产科杂志,2006,22(6):424-426. 被引量:6
-
4杨秉辉,夏景林.原发性肝癌的临床诊断与分期标准[J].中华肝脏病杂志,2001,9(6):324-324. 被引量:1017
-
5Fu-Sheng Wang Ming-Xu Liu Bing Zhang Ming Shi Zhou-Yun Lei Wen-Bing Sun Qing-You Du Ju-Mei Chen,Division of Biological Engineering,Beijing Institute of Infectious Diseases,Beijing 100039,China Wen-Bing Sun,Department of Surgery,Beijing Hospital of Infectious Diseases,Beijing 100039,China.Antitumor activities of human autologous cytokineinduced killer(CIK)cells against hepatocellular carcinoma cells in vitro and in vivo[J].World Journal of Gastroenterology,2002,8(3):464-468. 被引量:107
-
6李艺,昌晓红,崔恒,杨文兰,冯捷,魏丽惠.卵巢癌抗独特型微抗体主动免疫治疗卵巢癌动物实验[J].中国医学科学院学报,2003,25(4):451-456. 被引量:11
-
7JunQian,Gan-ShengFeng,ThomasVogl.Combined interventional therapies of hepatocellular carcinoma[J].World Journal of Gastroenterology,2003,9(9):1885-1891. 被引量:51
-
8吴沛宏,张福君.原发性肝细胞癌介入治疗基本模式的转变——经动脉导管栓塞化疗序贯联合消融治疗[J].中华放射学杂志,2003,37(10):870-871. 被引量:25
-
9吴沛宏,张福君,赵明,范卫君,黄金华,顾仰葵,李立.肝动脉栓塞化疗联合CT导向射频消融术治疗中、晚期肝癌的评价[J].中华放射学杂志,2003,37(10):901-904. 被引量:112
-
10杨秉辉,夏景林,黄力文,汤钊猷,陈敏山,李锦清,梁安民,莫钦国,卢辉山,戴朝六,严律南,于志坚,饶荣生,黎乐群,苏智雄,方壮伟.我国肝癌“临床相”30年的变迁——原发性肝癌3250例的对比研究[J].中华医学杂志,2003,83(12):1053-1057. 被引量:89
共引文献58
-
1孙振纲,陈孝平,黄志勇,杨国华,关键,胡道予,穆拉德,夏喜刚,李高鹏,张万广,李震.肝动脉灌注碘油羟基磷灰石纳米粒对兔VX2肝肿瘤细胞凋亡、增生及血管形成的影响[J].中华医学杂志,2007,87(6):409-413. 被引量:12
-
2鲁光平(综述),于志坚(审校).肝细胞癌血管生成调控与抗血管治疗进展[J].国际肿瘤学杂志,2007,34(8):605-608. 被引量:3
-
3杨波,脱朝伟,张宁,刘秋珍.CIK细胞对人原发性胃恶性淋巴瘤生长及肝转移的抑制作用[J].解放军医学杂志,2007,32(11):1126-1129. 被引量:3
-
4贾克东,杨建英,赖全图,刘晖,罗斌.射频消融治疗肝癌的近期疗效观察[J].实用肝脏病杂志,2007,10(6):413-416. 被引量:7
-
5杨葳,沈志奇,王俊懿,王大鹏,罗社文,高锦,徐铭宝.我国新型肿瘤细胞治疗方法CIK的研究与应用现状[J].科技导报,2008,26(6):73-77. 被引量:16
-
6杨甲梅,胡明华.应重视肝癌综合治疗的模式及其疗效[J].中华医学杂志,2008,88(36):2521-2523. 被引量:2
-
7高恒军,梁惠宏,陈敏山,彭振维,张耀军,黎鹏,庞雄昊,张亚奇,李锦清.射频消融联合经导管肝动脉栓塞化疗治疗肝癌疗效分析[J].中华医学杂志,2008,88(36):2529-2532. 被引量:27
-
8张志凯,祁岩超.健康人和肿瘤患者CIK细胞的生物学特性[J].中国热带医学,2009,9(2):253-254. 被引量:11
-
9吴沛宏.原发性肝癌的微创治疗与多学科综合治疗[J].中华生物医学工程杂志,2009,15(1):1-3. 被引量:1
-
10李旺,黄子林,张亮,赵明,吴沛宏.经导管动脉栓塞化疗联合射频消融和细胞因子诱导的杀伤细胞输注治疗小肝癌[J].中华生物医学工程杂志,2009,15(1):4-8. 被引量:3
同被引文献19
-
1Kryczek,I.,S.Wei,G.Zhu,et al.Relationship between B7-H4,regulatory T cells,and patient outcome in human ovarian carcinoma.Cancer Res,2007,67(18):8900-8905.
-
2Wolf,D.,A.M.Wolf,H.Rumpold,et al.The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.Clin Cancer Res,2005,11(23):8326-8331.
-
3Barnett,J.C.,S.M.Bean,R.S.Whitoker,et al.Ovarian cancer tumor infiltrating T-regulatory(T(reg))cells are associated with a metastatic phenotype.Gynecol Oncol,116(3):556-562.
-
4Wei,S.,I.Kryczek,R.P.Edwards,et al.Interleukin-2 aclministration alters the CD4+FOXP3+T-cell pool and tumor trafficking in patients with ovarian carcinoma.Cancer Res,2007,67(15):7487-7494.
-
5Nizar,S.,J.Copier,B.Meyer,et al.T-regulatory cell modulation:the future of cancer immunotherapy? Br J Cancer,2009,100(11):1697-1703.
-
6Hodi,F.S.,M.C.Mihm,R.J.Soiffer,et al.Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients.Proc Natl Acad Sci U S A,2003,100(8):4712-4717.
-
7Kandalaft,L.E.,N:Singh,J.B.Liao,et al.The emergence of immunomedulation:combinatorial immunochemotherapy opportunities for the next decade.Gynecol Oncol,116(2):222-233.
-
8Curiel,T.J.,Regulatory T cells and treatment of cancer.Curr Opin Immunol,2008,20(2):241-246.
-
9Liu,B.,J.Nash,C.Runowicz,et al.Ovarian cancer immunotherapy:opportunities,progresses and challenges.J Hematol Oncol,3:7.
-
10Barnett,B.,I.Kryczek,P.Cheng,et al.Regulatory T cells in ovarian cancer:biology and therapeutic potential.Am J Reprod Immunol,2005,54(6):369-377.
二级引证文献15
-
1郎巍,汪君,王雪野,葛平信,徐亚香.卵巢癌患者外周血CD4^+ CD25^(high)调节性T细胞及Foxp3的检测及临床意义[J].中国妇幼保健,2011,26(19):2981-2983. 被引量:1
-
2闫会苓,马丹,卢雯平.益气活血解毒方对晚期卵巢癌患者免疫调节的影响[J].中国中医药信息杂志,2016,23(1):27-30. 被引量:16
-
3董云峰,郭海.热疗联合放化疗治疗局部晚期直肠癌的疗效观察[J].中国癌症防治杂志,2015,7(6):425-428. 被引量:2
-
4张宝月,张俊农.表皮生长因子受体酪氨酸激酶抑制剂厄洛替尼联合山奈酚诱导卵巢癌细胞凋亡的协同机制[J].吉林大学学报(医学版),2016,42(1):31-35. 被引量:10
-
5孙洁,杨素芬,白图门,李梅,董迅,陈小萍.卵巢癌患者腹水及外周血CD4^+CD25^+调节性T细胞含量及抑制功能的研究[J].中国性科学,2016,25(2):17-19. 被引量:4
-
6智会,李震.热疗联合放化疗治疗局部晚期直肠癌的疗效[J].中国继续医学教育,2016,8(10):76-77. 被引量:1
-
7贺清波,赵西侠,张骏,徐静,闫涛.紫杉醇静脉滴注联合铂类腹腔灌注治疗卵巢癌疗效和安全性的Meta分析[J].解放军药学学报,2016,32(4):364-367. 被引量:3
-
8温平.浅析晚期老年卵巢癌的临床治疗效果观察[J].中国医药指南,2017,15(2):20-21.
-
9曲世楠.紫杉醇联合顺铂腹腔和静脉对晚期卵巢癌的治疗效果[J].中国冶金工业医学杂志,2017,34(3):319-320.
-
10王海燕,许芙蓉,王红,胡昌华,蒋红梅.紫杉醇联合顺铂腹腔热灌注在晚期卵巢癌患者中的应用及对生存期的影响[J].肿瘤药学,2017,7(3):315-318. 被引量:7
-
1杨莉云.卵巢癌CT诊断的临床价值(附21例报告)[J].贵州医药,2008,32(10):910-911. 被引量:2
-
2王斌,田华琴.中医药在原发性肝癌介入治疗中的作用[J].陕西中医,2007,28(5):635-637. 被引量:1
-
3金少纯,钟燎原,王仁和,罗虹雨.胰腺癌67例分析[J].中华腹部疾病杂志,2004,4(9):663-664.
-
4胡德荣.近20年我国肿瘤死亡率上升29.42%[J].老年健康,2011(4):5-5.
-
5廖渝,蒋飞龙,陈兴文.肿瘤标志物联检在肝癌诊断中的价值[J].中国误诊学杂志,2008,8(1):94-95. 被引量:4
-
6任志刚,张瑜.胆囊癌18例临床诊治分析[J].包头医学院学报,2002,18(4):303-304.
-
7吴天鹏,刘铭球.第五讲 肿瘤的病因及可能的发病机理[J].中国乡村医生,1993(5):20-21.
-
8王方华.肝癌的早期诊断和治疗进展[J].中国现代普通外科进展,2012,15(12):983-985. 被引量:8
-
9刘变英.胃癌的早期诊断[J].人人健康,2011(21):22-22.
-
10王明明,徐亮,夏冬.Cox-2在大肠癌耐药机理中的研究进展[J].现代临床医学,2011,37(6):406-407. 被引量:3