摘要
目的:探讨绝经后妇女取器术前宫颈准备3种方法的效果。方法:收集绝经后妇女取器183例相关资料,分为3组。A组:术前3天早、晚各口服米非司酮片25mg,2次间隔12h,服药前后空腹2h,总量150mg,手术当日术前2h阴道后穹隆置米索前列醇400μg;B组:术前2h阴道后穹隆置米索前列醇400μg;C组:术前1周口服尼尔雌醇片,4mg/次,1次/d。比较3组取器术效果。结果:A组宫颈软化程度最好,均顺利取器,手术时间短,出血少。B组次之,部分取器困难,两组宫口扩张大小、手术时间、出血量及成功率与C组比较差异均有统计学意义(P<0.05)。结论:米非司酮配伍米索前列醇用于绝经后取器,可提高手术成功率,减轻手术痛苦,且安全、有效、副反应少,可作为绝经后妇女取器的术前用药。
Objective： To compare the effects of 3 kinds of preoperative cervical preparations for removal of intrauterine devices（IUDs） in the postmenopausal women.Methods： A total of 183 women was recruited and allocated to 3 groups： group A： women were given mifepristone 25mg orally at 12h interval for 3 consecutive days and misoprostol 0.4mg vaginally 2 hours before operation in the hospital;group B： women were given misoprostol 0.4mg vaginally 2 hours before operation in the hospital;group C： women were given nilestriol 4mg per day orally for 7 consecutive days.The effects of preoperative cervical preparations in 3 groups were compared.Results： In group A,all of the IUDs were removed smoothly because of the best effects of cervical softening,and the duration of operation was short,and the amount of blood loss was less.The effect of preoperative cervical preparation in group B was inferior to that in group A.The degree of cervical dilation,the duration of operation,the amount of blood loss and the successful rate in group A and B were significantly superior than those in group C（P0.05）.Conclusion： The mifepristone and misoprostol regimen used for removal of IUDs in the postmenopausal women can improve the success rate of operation,and alleviate the pain of women due to its safety,validity and less side effects.It should be used for the preoperative preparations for removal of IUDs in the postmenopausal women.
出处
《中国计划生育学杂志》
北大核心
2010年第3期171-173,共3页
Chinese Journal of Family Planning
