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头孢米诺钠皮试阴性患者使用该药出现过敏性休克死亡 被引量:6

Death from anaphylactic shock following administration of cefminox sodium in a patient with a negative cefminox sodium skin test
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摘要 1例68岁前列腺增生患者因行前列腺电切术后预防感染,给予头孢米诺钠3.0 g+0.9%氯化钠注射液250 ml,2次/d静脉滴注;阿莫西林-克拉维酸钾1.8 g+0.9%氯化钠注射液250 ml,2次/d静脉滴注。连用5 d。第6天,静脉滴注头孢米诺钠约10 ml后,患者突然出现头晕、恶心、胸闷、大汗淋漓、脉搏细速、血压测不出。立即停止输液,给予吸氧、皮下注射肾上腺素、静脉推注地塞米松、静脉滴注多巴胺等治疗。但患者病情加重,意识丧失,呈深昏迷状态,无自主呼吸。最终,患者经抢救无效死亡。 A 68-year-old man with prostatic hyperplasia received an IV infusion of cefminox sodium 3.0 g in 0.9% sodium chloride 250 ml twice daily and an IV infusion of amoxicillin and clavulanate potassium 1.8 g in 0.9% sodium chloride 250 ml twice daily for prevention of infections for 5 days.On day 6,after infusion of 10 ml of cefminox sodium,the patient developed dizziness,nausea,chest distress,polyhidrosis,weak pulse,undetectable blood pressure.The infusion was stopped immediately.Oxygen inhalation,SC adrenaline,an IV push of dexamethasone,and an IV infusion of dopamine were given.Subsequently,his symptoms worsened and he presented with unconsciousness,deep coma without spontaneously breathing.Finally,the patient died despite resuscitation attempts.
出处 《药物不良反应杂志》 2009年第6期431-431,共1页 Adverse Drug Reactions Journal
关键词 头孢米诺钠 不良反应 过敏性休克 cefminox adverse reactions anaphylactic shock
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