摘要
目的通过对比分析奥美拉唑和泮托拉唑治疗消化性溃疡的临床效果,为临床医师选择最佳治疗药物提供依据。方法选择本院自2002年10月至2008年12月收治210例消化性溃疡,按用药方案抽取质子泵抑制剂药物奥美拉唑102例及泮托拉唑108例。分析对比两组治疗对溃疡愈合,症状缓解,幽门螺旋菌(Hp)的根治率等。结果奥美拉唑与泮托拉唑的治疗效果总有效率分别为84.3%和88.9%,泮托拉唑治疗消化性溃疡在Hp根除率,溃疡的愈合率方面比较,明显高于奥美拉唑,且差异有显著性。结论泮托拉唑是治疗消化性溃疡比较理想的药物。
Objective To investigate the clinical efficacy of omeprazole and pantoprazole in treatment of peptic ulcer and provide drug information for clinicists.Methods 210 cases with peptic ulcer were selected as treatment groups,102 of them were treated with omeprazole ahd the other 108 were treated with pantoprazole.Results Effective percentage was 88.9%in pantoprazole group,compared with that in the omeprazole group was 84.3%,the differences weres ignificant（P〈0.05）.And pantoprazole was better at ulcer healing and eradication of Hp,the differences weresignificant（P〈0.05）.Conclusion Both of the 2 drugs is app licable to patients with peptic ulcer,but a better effect of pantoprazole.
出处
《中国实用医药》
2010年第7期27-28,共2页
China Practical Medicine
