摘要
目的探讨A型肉毒毒素治疗面肌痉挛的疗效。方法将52例面肌痉挛患者依据接受A型肉毒毒素治疗的次数分为两组:首次治疗组32例、长期重复治疗组(连续接受4次及4次以上A型肉毒毒素治疗)20例。本次注射A型肉毒毒素后随访6个月,比较两组在起效时间、达峰时间、疗效等级等方面的差别。结果两组患者注射A型肉毒毒素后在起效时间、达峰时间、疗效等级等方面比较均无明显差异。结论长期重复应用A型肉毒毒素治疗面肌痉挛疗效依然显著,在起效时间、疗效等级等方面保持不变。
Objective To observe the effectiveness of botulinum toxin （BTX）injection for hemifacial spasm （HFS）. Methods 52 patients with hemifacial spasm were divided into two groups based on the times of BTX injection： first BTX injection group（32 patients） and long-term repeat BTX injection group（received 4 times BTX injection or more consecutively,20 patients）. Following up for 6 months,time to onset effect, time of peak effect, and grades of effect were compared between the two groups. Results There was no difference in the time to onset effect,time of peak effect and grades of effect between the two groups. Conclusion The effect of BTX injection in HFS patients is still significant,and the time to onset effect,time of peak effect,grades of effect still remain unchanged.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第6期653-655,共3页
Chongqing medicine
