摘要
目的探讨血清N末端B型钠尿肽原（NT-proBNP）在不明原因呼吸困难病因分析的临床意义。方法针对急诊入院不明原因呼吸困难的患者,应用电化学发光法检测患者血清NT-proBNP的浓度;详细追问病史、体格检查,结合心电图、心脏彩超、胸片、肺功能测定等相关检查,进一步明确患者呼吸困难的原因。结果心源性呼吸困难患者血清NT-proBNP浓度在829.20-18700.50 pg/ml间,NT-proBNP呈偏态分布,中位数水平分别为4474.80 pg/ml,非心源性呼吸困难患者血清NT-proBNP浓度在10.20-389.50 pg/ml间,NT-pro BNP呈偏态分布,中位数水平分别为174.20 pg/ml,两组患者血清NT-proBNP浓度中位数比较差异有统计学意义（P值〈0.05）。结论血清NT-proBNP浓度在鉴别心源性或非心源性呼吸困难中有重要意义。
Objective To study the clinical significance of NT-proBNP in analysis of dyspnea with unkown cause. Methods To detect the serum densities of NT-proBNP by electrochemiluminescence for the patients with dyspnea of unknown cause on emergency admission.By tracing the detailed history of illness,physical examination,combined with the related tests of cardiogram,cardiac color doppler sonography,sternum,lung function to clarify the causes of dyspnea.Results The serum NT-proBNP densities of the cardiac dyspnea patients were between 829.20-18700.50 pg/ml with a skew distribution of NT-proBNP densities,median being 4474.80 pg/ml,while in non-cardiac dyspnea patient group,the serum NT-proBNP densities were between 10.20-389.50 pg/ml with a skew distribution,mediant being 174.20 pg/ml.By comparison of the two medians of the NT-proBNP densities in the two groups,it is significant in statistics.Conclusions The serum NT-proBNP concentration is greatly significant in discerning of cardiac or non-cardiac dyspnea.
出处
《临床医学》
CAS
2010年第1期4-5,共2页
Clinical Medicine
