摘要
目的:了解我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2007～2008年收集的213例ADR报告,采用Excel电子表格和手工筛查的方式,按照患者的性别、年龄、药品类别、剂型、ADR累及器官或系统及临床表现等进行统计、分析。结果:213例报告中,女性(128例)多于男性(85例);涉及药品128种;ADR主要由抗微生物药引起,其次是中药制剂;ADR表现主要是皮肤及其附件损害(30.09%)、消化系统损害(30.09%);用药剂型主要是注射剂(65.73%);18.31%的ADR需要治疗。结论:临床应加强中药制剂和抗微生物药的监测,重视中药和喹诺酮类药物的ADR。
OBJECTIVE： To probe into the characteristics and regularity of adverse drug reactions occurred in our hospital. METHODS： A total of 213 ADR cases reported in our hospital from 2007 to 2008 were analyzed statistically in respect of patients＇ age and gender, category of drug, dosage form, organs and systems involved in ADR and clinical manifestation by means of Excel table and manual selection. RESULTS： 128 kinds of drugs were involved in the 213 ADR cases, leading the first 2 places in terms of ADR incidence were antibiotics and TCM preparation. 128 cases were women beyond 85 cases of men. The ADR appeared mainly as lesions of skin and its appendants （30.09%） and digestive system （30.09%）. 65.73% of dosage form were injection and 18.31% of ADR need treatment. CONCLUSION： Great importance should be attached to safety monitoring of antibiotics and TCM preparation and ADR induced by TCM preparation and quinolones.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第10期924-925,共2页
China Pharmacy
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
