摘要
以3-氰基吡啶为原料,经氧化、氯化和水解反应合成了2-氯烟酸,优化了各步反应条件,产品纯度为99.5%,总收率达77.2%。产品结构经红外光谱和质谱进行了表征。
2-Chloronicotinic acid was synthesized from 3-cyanopyridine by the reaction of oxidation, chlorination and hydrolysis. The reaction conditions were optimized. The total yield and purity of the product reached 77. 2%, 99.5%, respectively. The structure of the product was identified by IR and MS.
出处
《化学与生物工程》
CAS
2010年第4期36-37,共2页
Chemistry & Bioengineering
关键词
3-氰基吡啶
2-氯烟酸
合成
3-cyanopyridine
2-chloronicotinic acid
synthesis
