摘要
分子靶向治疗作为癌症治疗的新手段,以其低毒副作用和高效率的治疗效果正成为癌症治疗研究的热点。在生物体内有许多可以作为癌症治疗靶点的分子,这些靶点分子位于癌细胞的不同位置:细胞膜、细胞质、细胞核及细胞外基质。本文综述了癌症分子靶向治疗领域的研究现状及药物研发现状,为癌症分子靶向治疗的研究提供参考。
Molecular-targeted therapy is a newly developed approach for cancer therapy. With the advantages of lower side effects and higher performance,this approach has become a critical focus of cancer research. There are various molecules that can be treated as therapeutic targets for cancer. These molecules are located in different compartments of cancer cells,such as the cell membrane,cytoplasm,nucleus,and extracellular matrix. In this review,we mainly discussed the current progress in molecular-targeted therapy for cancers and the development of new drugs in this field.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2010年第3期370-375,共6页
Chinese Journal of Cancer
基金
国家自然科学基金项目(No.30870683)~~
关键词
癌症
分子靶向
治疗
药物
Cancer
molecular targeted
therapy
drugs
