摘要
目的根据硬脑膜静脉窦血栓发病急缓将其分为急性和非急性两型,分析它们的临床特点及治疗措施。方法回顾性分析15例硬脑膜静脉窦血栓形成病例,比较其临床症状、影像学表现、病程特点、治疗方式和治疗效果。结果15例患者中,6例为急性起病,症状较重,常伴有颅内出血或静脉性脑梗死,采用内外科综合治疗,3例好转,3例在4 d内恶化或死亡;9例非急性起病,症状较轻,很少并发颅内出血,采用抗凝治疗,均好转。结论硬脑膜静脉窦血栓可分为急性起病和非急性起病两型,前者预后较差,通过脑静脉造影早期诊断和综合治疗是降低其死亡率的关键,后者预后较好,仅需抗凝治疗。
Objective Based on clinical onset,dural sinus thromboses（DST） are classified into acute and non-acute types,of which the clinical features and therapeutic measurements are analyzed respectively.Methods Fifteen cases of DST were retrospectively reviewed and compared in clinical symptoms,radiographic manifestations,disease courses,and treatment modalities and effects.Results Six out of 15 cases had acute onset and severe phenotypes,often combined with cerebral hemorrhage and venous infarction.Moreover,from those 6,3 patients recovered and 3 cases were deteriorated or died in 4 days after comprehensive surgical treatments.All of the 9 cases of non-acute onset,who had mild symptoms and rarely complicated by intracranial hemorrhage,recovered after treatment with anticoagulation therapy.Conclusion DST can be divided into acute and non-acute types.The acute type is highly likely with poor prognosis.Early diagnoses via cerebral venography and comprehensive treatments are critical to reduce the mortality.In contrast,the cases of non-acute DST have a better prognosis and can be treated well with anticoagulation therapy.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2010年第2期261-265,共5页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
关键词
硬脑膜静脉窦血栓
脑静脉造影
抗凝
手术
dural sinus thrombosis
cerebral venography
anticoagulation
operation
