摘要
目的:探讨不同时机使用丹参制剂对THA术后失血量和DVT发生率的影响。方法:2003年1月～2007年12月对我院行单侧初次THA的118例患者随机分为术前用药组和术后用药组,术前用药组68例,术后用药组50例。通过Gross方程,根据患者身高、体重、术前术后红细胞压积和输血量,计算2组患者的总失血量和隐性失血量,并比较2组DVT的发生率。结果:术前用药组总失血量平均1756ml,隐性失血量平均523ml,术后用药组总失血量平均1398ml,隐性失血量410ml,2组比较差异有统计学意义(P<0.05)。THA术后DVT发生率,术前用药组为22.1%,术后用药组为14.0%,两组比较差异无统计学意义(P>0.05)。结论:术前使用丹参制剂可增加THA手术的总失血量和隐性失血量,使用丹参制剂的时机对术后DVT的发生率无影响,术后使用丹参制剂更安全。
Objective：To investigate the effect of salvia miltiorrhiza on blood loss and incidence rates of deep vein thrombosis（DVT） in total hip arthroplasty（THA）.Methods：From January 2003 to December 2007,118 patients with THA were treated by salvia miltiorrhiza,68 preoperatively and 50 postoperatively.According to Gross formula,the total blood loss and the hidden blood loss were calculated depending on height,weight,pre-and post-operation hematocrit,and blood transfusion volume.And the incidence rates of DVT were observed.Results：In preoperative treatment group,the average total blood loss was 1756ml,and the hidden blood loss was 523ml.While in postoperative treatment group,the average total blood loss was 1398ml,and the hidden blood loss was 410ml.There were significant differences between the two groups（P〈0.05）.The incidence rate of DVT was 22.1% and 14.0% in preoperative and postoperative treatment groups,respectively.No significant difference was found between the two groups in the incidence rate of DVT（P〉0.05）.Conclusion：Preoperative use of salvia miltiorrhiza can increase the total blood loss and hidden blood loss in THA operation.The timing of salvia miltiorrhiza has influence on the incidence rates of DVT.Postoperative application of salvia miltiorrhiza is safer than preoperative application.
出处
《中国中医骨伤科杂志》
CAS
2010年第4期27-28,31,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
关节成形术
置换
髋
失血
深静脉血栓
丹参
Arthroplasty
Replacement
Hip
Blood loss
Deep vein thrombosis
Salvia miltiorrhiza
