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内脂素及肿瘤坏死因子-α与2型糖尿病大血管并发症的关系 被引量:15

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摘要 目的探讨内脂素及肿瘤坏死因子α(TNF-α)与2型糖尿病患者大血管并发症的关系。方法根据2型糖尿病患者是否存在大血管病变,分为大血管病变组和非大血管病变组,并与正常对照组比较。ELISA法测定血清内脂素、TNF-α水平。结果大血管病变组和非大血管病变组血清内脂素、TNF-α水平均明显高于对照组(P<0.01),以大血管病变组为著(P<0.05或<0.01)。Logistic回归分析显示,内脂素、TNF-α进入回归方程。结论内脂素、TNF-α是2型糖尿病大血管并发症的重要危险因素。
出处 《山东医药》 CAS 北大核心 2010年第17期48-50,共3页 Shandong Medical Journal
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