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隧道式TURP治疗伴膀胱出口梗阻的晚期前列腺癌 被引量:3

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摘要 目的探讨隧道式经尿道前列腺切除术(TURP)治疗伴膀胱出口梗阻(BOO)的晚期前列腺癌的临床疗效及手术时机的选择。方法回顾分析2002年7月至2008年8月收治的伴BOO症状的晚期前列腺癌患者58例,年龄63~87岁,平均74岁。均经影像学和前列腺穿刺活检等系列检查明确诊断为(T3~T4)前列腺癌,对21例采用一期隧道式TURP和双侧睾丸切除术,术后行内分泌治疗;对经睾丸切除和抗雄激素联合治疗3个月的37例中仍有排尿困难的14例采用隧道式TURP治疗。结果35例患者隧道式TURP手术均成功,手术时间(65±25)min,切除前列腺平均重量42g。随访2~5年,死亡14例,其中死于前列腺癌10例,平均生存38个月,死于其他原因4例。患者术后排尿困难症状明显改善。37例患者采用内分泌治疗3个月,23例患者最终能自行排尿。结论隧道式TURP是治疗伴BOO的晚期前列腺癌的安全、简便易行、有效方法之一,虽不能改变患者的临床结局,但可迅速缓解梗阻症状,明显提高患者生活质量。对部分患者依病情可先行内分泌治疗,根据治疗效果再决定是否采用TURP处理。
出处 《中国临床研究》 CAS 2010年第5期384-385,共2页 Chinese Journal of Clinical Research
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共引文献33

同被引文献31

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