摘要
目的:探讨理气调补汤对运动性疲劳大鼠下丘脑-垂体-肾上腺轴的调节作用。方法:30只健康雄性SD大鼠随机分为3组。采用大鼠游泳运动训练方式,观察大鼠最后1次力竭游泳的力竭时间、血清皮质酮、睾酮、血清和下丘脑β内啡肽含量等指标。结果:理气调补汤可以延长大鼠游泳力竭的时间(P<0.01),提高血清睾酮含量;降低血清β内啡肽含量。结论:理气调补汤可以改善运动性疲劳大鼠下丘脑-垂体-肾上腺轴的功能,从而起到预防运动性疲劳的作用。
Objective：To observe and to discuss the effect of Liqi Tiaobu Tang on hypothalamic-pituitaryadrenal axis in the rat of fatigue induced by exercise. Method：30 male SD rats were randomly divided into 3 groups. Ⅰ and Ⅱ groups are all trained for 6 weeks with swimming. The last exhaustive swimming time,serum corticosterone,testosterone,and hypothalamic β-endorphin were observed. Result：Liqi Tiaobu Tang could extend the time for exhaustive swimming in rats（P 0. 01）,increase the content of T,and decrease the content of serum β-endorphin. Conclusion：Liqi Tiaobu Tang improves hypothalamus-pituitary-adrenal axis function in the rat of fatigue induced by exercise. It may prevent the exercise fatigue.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第5期139-141,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
北京市教育委员会人才强教项目资助课题(PXM2008-014206-053361)
关键词
理气调补汤
运动性疲劳
下丘脑-垂体-肾上腺轴
Liqi Tiaobu Tang
exercise-induced fatigue
hypothalamic-pituitary-adrenal axis
