摘要
自从20多年前Hosobuchi首次发现脊髓电刺激具有显著增加脑血流的作用后,该技术即在脑缺血治疗领域引起了广泛关注。学者进行了大量动物实验和临床研究,使其成为继溶栓和介入治疗后的又一研究热点。文章对脊髓电刺激在脑缺血保护中的研究历史、作用机制和临床应用现状进行了综述。
Since Hosobuchi first found that spinal cord stimulation had the effect of significantly increasing cerebral blood flow (CBF) more than two decades ago, spinal cord stimulation had attracted wide attention in the field of treating cerebral ischemia. A large number of animal and clinical studies have been performed in this field, which make it another research focus following thrombolysis and interventional therapy. This article reviews the research history, mechanisms, and current status of clinical applications of spinal cord stimulation in cerebral ischemia protection.
出处
《国际脑血管病杂志》
北大核心
2010年第4期286-290,共5页
International Journal of Cerebrovascular Diseases
关键词
电刺激疗法
脊髓
脑缺血
脑血管循环
血管舒张
血管痉挛
颅内
交感神经系统
Electric stimulation therapy
Spinal cord
Brain ischemia
Cerebrovascular circulation
Vasodilation
Vasospasm, intracranial
Sympathetic nervous system